Evidence map›Paper›PMID 30046103›Full record

ArticleNature2018

Retraction Note: Selective killing of cancer cells by a small molecule targeting the stress response to ROS.

Lakshmi Raj, Takao Ide, Aditi U Gurkar, Michael Foley, Monica Schenone, Xiaoyu Li, Nicola J Tolliday, Todd R Golub, Steven A Carr, Alykhan F Shamji and 4 more

Abstract readRetraction Notice
In one paragraph

Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Lakshmi RajCutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA.
Takao IdeCutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA.
Aditi U GurkarCutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA.
Michael FoleyBroad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
Monica SchenoneBroad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
Xiaoyu LiBroad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
Nicola J TollidayBroad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
Todd R GolubBroad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
Steven A CarrBroad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
Alykhan F ShamjiBroad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
Andrew M SternBroad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA.
Anna MandinovaCutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA. amandinova@partners.org.
Stuart L SchreiberBroad Institute of Harvard and MIT, 7 Cambridge Center, Massachusetts, 02142, USA. stuart_schreiber@harvard.edu.
Sam W LeeCutaneous Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Building 149 13th Street, Charlestown, Massachusetts, 02129, USA. swlee@partners.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This Letter is being retracted owing to issues with Fig. 1d and Supplementary Fig. 31b, and the unavailability of original data for these figures that raise concerns regarding the integrity of the figures. Nature published two previous corrections related to this Letter

Identifiers

PMID30046103
PMCPMC6148382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.