Evidence map›Paper›PMID 30045912›Full record

GuidelineBMJ (Clinical research ed.)2018

Patent foramen ovale closure, antiplatelet therapy or anticoagulation therapy alone for management of cryptogenic stroke? A clinical practice guideline.

Ton Kuijpers, Frederick A Spencer, Reed A C Siemieniuk, Per O Vandvik, Catherine M Otto, Lyubov Lytvyn, Hassan Mir, Albert Y Jin, Veena Manja, Ganesan Karthikeyan and 10 more

Registry-linked trialOpen access · hybridAbstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in BMJ (Clinical research ed.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06504121 (PFO tRanscatether Occlusion Long-term Outcomes National Group), which is not on this map. Cited by 32 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 4 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06504121 completednot on this map

PFO tRanscatether Occlusion Long-term Outcomes National Group (PROLONG) Registry

TypeobservationalSponsorIRCCS Ospedale San RaffaeleRan1999 to 2024Enrolled1,360ConditionsPatent Foramen Ovale, Stroke, Cryptogenic, Transient Ischaemic Attack Due to Embolism, Atrial Fibrillation New OnsetArmsSeptal Occluder Device
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 89 citations in OpenAlex.

  1. A systematic review and synthesis of global stroke guidelines on behalf of the World Stroke Organization.International journal of stroke : official journal of the International Stroke Society · 2023
    Pooled it
  2. New-onset atrial fibrillation following percutaneous closure of patent foramen ovale: a systematic review and meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 15 institutions in 8 countries.

Ton KuijpersDepartment of guideline development and research, Dutch College of General Practitioners, Utrecht, The Netherlands t.kuijpers@nhg.org.
Frederick A SpencerMcMaster University, Hamilton, Canada.
Reed A C SiemieniukDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada L8S 4L8.
Per O VandvikNorwegian Institute of Public Health, Oslo, Norway.
Catherine M OttoUniversity of Washington, Seattle, District of Colombia, USA.
Lyubov LytvynMcMaster University, Hamilton, Canada.
Hassan MirMcMaster University, Hamilton, Canada.
Albert Y JinDivision of Neurology, Department of Medicine, Queen's University, Kingston, Ontario, Canada.
Veena ManjaUniversity of California Davis, Sacramento, CA, USA.
Ganesan KarthikeyanAll India Institute of Medical Sciences, New Delhi, India.
Elke HoendermisUniversity Medical Center of Groningen, Groningen, The Netherlands.
Janet MartinDepartments of Anesthesia & Perioperative Medicine, and Epidemiology & Biostatistics, Western University, London, Canada.
Sebastian CarballoDivision General Internal Medicine, University Hospitals of Geneva, CH-1211, Geneva, Switzerland.
Martin O'DonnellNUI Galway, Galway, Ireland.
Trond VartdalOslo University Hospital, Oslo, Norway.
Christine BaxterLas Vegas, Nevada, USA.
Bray Patrick-LakeBoulder, Colorado, USA.
Joanie ScottWelwyn, Hertfordshire, UK.
Thomas AgoritsasDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada L8S 4L8.
Gordon GuyattMcMaster University, Hamilton, Canada.
McMaster University · CAImpact · CAAll India Institute of Medical Sciences · INColorado Sleep Institute · USDutch College of General Practitioners · NLHertfordshire Community NHS Trust · GBInnlandet Hospital Trust · NOOllscoil na Gaillimhe – University of Galway · IEOslo University Hospital · NOQueen's University · CAUniversity Hospital of Geneva · CHUniversity Medical Center Groningen · NLUniversity of California, Davis · USUniversity of Washington · USWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnticoagulantsClinical Decision-MakingForamen Ovale, PatentHumansPlatelet Aggregation InhibitorsStrokeSystematic Reviews as TopicAnticoagulantsPlatelet Aggregation Inhibitors

Identifiers

PMID30045912
PMCPMC6058599
OpenAlexW2883563162

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.