Evidence map›Paper›PMID 30045772›Full record

ArticleSystematic reviews2018

Adherence to prenatal iron-folic acid supplementation in low- and middle-income countries (LMIC): a protocol for systematic review and meta-analysis.

Mohammed Akibu, Tesfalidet Tekelab, Abdella Amano, Merga Besho, Stephanie Grutzmacher, Mesfin Tadese, Tesfa Dejenie Habtewold

Open access · goldAbstract read
In one paragraph

Article in Systematic reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Mohammed AkibuInstitute of Medicine and Health Science, Debre Berhan University, Debre Berhan, Ethiopia. mahammedakibu@gmail.com.
Tesfalidet TekelabResearch Centre for Generational Health and Ageing at the Hunter Medical Research Institute, University of Newcastle, Callaghan, Australia.
Abdella AmanoCollege of Medicine and Health Science, School of Public Health, Hawassa University, Hawassa, Ethiopia.
Merga BeshoCollege of Medicine and Health Science, Wollaga University, Nekemte, Ethiopia.
Stephanie GrutzmacherSchool of Biological and Population Health Sciences, Oregon State University, Corvallis, USA.
Mesfin TadeseInstitute of Medicine and Health Science, Debre Berhan University, Debre Berhan, Ethiopia.
Tesfa Dejenie HabtewoldDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0003-4476-518X
Debre Berhan University · ETWollega University · ETHawassa University · ETOregon State University · USUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDaily iron-folic acid supplementation reduces anemia and various adverse obstetric outcomes such as preterm delivery, low birthweight, hemorrhage, and perinatal and maternal morbidity and mortality. However, its supplementation has not been successful that attributed to several determinants including poor adherence. Therefore, we aimed to conduct a systematic review and meta-analysis on the prevalence and determinants of adherence to prenatal iron-folic acid supplementation in low- and middle-income countries. In addition, we will develop a conceptual framework in the context of low- and middle-income countries (LMIC). METHODS/

designWe will search PubMed, MEDLINE, EMBASE, EBSCO, Web of Science, SCOPUS, WHO Global Index Medicus, and African Journals Online (AJOL) databases to retrieve relevant literatures. Observational (i.e., case-control, cohort, cross-sectional, survey, and surveillance reports) and quasi-randomized and randomized controlled trial studies conducted in LMIC will be included. The Newcastle-Ottawa Scale (NOS) and Joanna Briggs Institute (JBI) critical appraisal checklist will be used to assess the quality of observational and randomized controlled trial studies respectively. The pooled prevalence and odds ratio of determinants of adherence will be generated using a weighted inverse-variance meta-analysis model. Statistical heterogeneity among studies will be assessed by Cochran's Q χ DISCUSSION: Contemporary evidence about the prevalence and determinants of adherence in LMIC will be synthesized to generate up-to-date knowledge. To our knowledge, this is the first systematic review. It would have substantial implications for researchers, clinicians, and policymakers for optimizing maternal and child health outcomes in LMIC. SYSTEMATIC REVIEW REGISTRATION: The protocol has been registered on International Prospective Register of Systematic Review (PROSPERO), University of York Center for Reviews and Dissemination ( https://www.crd.york.ac.uk/ ), registration number CRD42017080245 .

Indexed as

Dietary SupplementsFolic AcidIron, DietaryMedication AdherenceDeveloping CountriesFemaleHumansInfant, NewbornMeta-Analysis as TopicMicronutrientsPregnancyPregnancy ComplicationsPregnancy OutcomePrenatal CareSystematic Reviews as TopicFolic AcidIron, DietaryMicronutrientsFolateFolic acidIronMedication adherencePatient compliancePregnancyPrenatal carePrenatal Nutritional Physiological Phenomena

Identifiers

PMID30045772
PMCPMC6060532
OpenAlexW2884705930

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.