ArticleGenome biology2018
The healthy ageing gene expression signature for Alzheimer's disease diagnosis: a random sampling perspective.
Article in Genome biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Statistical knockoffs improve biomarker discovery from transcriptomic data.Briefings in bioinformatics · 2026Article
- Prediction Model for Pre-Eclampsia Using Gestational-Age-Specific Serum Creatinine Distribution.Biology · 2023Article
- Quantitative ultrasound for non-invasive evaluation of subclinical rejection in renal transplantation.European radiology · 2023Article
- Retracted: A Deep Neural Network for Estimating Low-Density Lipoprotein Cholesterol From Electronic Health Records: Real-Time Routine Clinical Application.JMIR medical informatics · 2021Article
- Robust Sampling of Defective Pathways in Alzheimer's Disease. Implications in Drug Repositioning.International journal of molecular sciences · 2020Article
- A statistical and biological response to an informatics appraisal of healthy aging gene signatures.Genome biology · 2019Article
- Avoiding common pitfalls in machine learning omic data science.Nature materials · 2019Article
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2 authors.
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Abstract
In a recent publication, Sood et al. (Genome Biol 16:185, 2015) presented a set of 150 probe sets that could be used in the diagnosis of Alzheimer's disease (AD) based on gene expression. We reproduce some of their experiments and show that their signature is indeed able to discriminate between AD and control patients using blood gene expression in two cohorts. We also show that its performance does not stand out compared to randomly sampled sets of 150 probe sets from the same array.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.