SynthesisCritical care (London, England)2018
Effect of decompressive laparotomy on organ function in patients with abdominal compartment syndrome: a systematic review and meta-analysis.
Synthesis in Critical care (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 70 citations in OpenAlex.
- Current Evidence on the Management of Non-occlusive Mesenteric Ischemia: A Comprehensive Narrative Review.Cureus · 2026Review
- Cumulative intra-abdominal pressure exposure and dynamic trajectories in ICU-admitted patients reveal prognostic determinants of severe acute pancreatitis.World journal of emergency surgery : WJES · 2025Article
- Nonsurgical Management of Abdominal Compartment Syndrome Using Transarterial Embolization and Percutaneous Catheter Drainage: A Case Report.Mayo Clinic proceedings. Innovations, quality & outcomes · 2025Article
- Awareness, knowledge and practices related to intra-abdominal hypertension and abdominal compartment syndrome among intensive care providers: a systematic scoping review.Annals of intensive care · 2025Review
- Successful treatment with decompressive laparotomy for abdominal compartment syndrome induced by asparaginase-associated pancreatitis in a pediatric patient with acute lymphoblastic leukemia: a case report.Translational pediatrics · 2025Article
- Increased intra-abdominal pressure linked to worse long-term prognosis among patients with orthotopic liver transplantation: a retrospective, observational study.BMC gastroenterology · 2025Observational
- Intra-abdominal hypertension/abdominal compartment syndrome of pediatric patients in critical care settings.Open medicine (Warsaw, Poland) · 2025Review
- International cross-sectional survey on current and updated definitions of intra-abdominal hypertension and abdominal compartment syndrome.World journal of emergency surgery : WJES · 2024Article
- Perioperative management of a patient with unexpectedly detected early-stage ovarian mucinous carcinoma combined with progressive bulbar paralysis: a case report and literature review.BMC women's health · 2024Review
- Underneath Images and Robots, Looking Deeper into the Pneumoperitoneum: A Narrative Review.Journal of clinical medicine · 2024Review
- Evaluating a novel vertical traction device for early closure in open abdomen management: a consecutive case series.Frontiers in surgery · 2024Article
- Characteristics and Outcome Analysis for Intensive Care Patients Undergoing Decompressive Laparotomy for Abdominal Compartment Syndrome: Impact of Extracorporeal Membrane Oxygenation Support.Journal of clinical medicine · 2023Article
- The Association Between Intra-abdominal Pressure and Diuretic Response in Heart Failure.Current heart failure reports · 2023Review
- Surgical decompression for the management of abdominal compartment syndrome with severe acute pancreatitis: A narrative review.World journal of gastrointestinal surgery · 2023Review
- Article
- [Noninvasive intra-abdominal pressure measurement].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2022Article
- Regulation of Key Immune-Related Genes in the Heart Following Burn Injury.Journal of personalized medicine · 2022Article
- Who would benefit from open abdomen in severe acute pancreatitis?-a matched case-control study.World journal of emergency surgery : WJES · 2021Article
- Management of intra-abdominal hypertension during ECMO: Total water-assisted colonoscopy as a step-up minimally invasive treatment, and a literature review.Endoscopy international open · 2021Article
- A Clinician's Guide to Management of Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Critically Ill Patients.Critical care (London, England) · 2020Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDecompressive laparotomy has been advised as potential treatment for abdominal compartment syndrome (ACS) when medical management fails; yet, the effect on parameters of organ function differs markedly in the published literature. In this study, we sought to investigate the effect of decompressive laparotomy on intra-abdominal pressure and organ function in critically ill adult and pediatric patients with ACS, specifically focusing on hemodynamic, respiratory, and kidney function and outcome.
methodsA systematic review and meta-analysis of the literature was performed. Articles reporting data on intra-abdominal pressure (IAP), hemodynamic (mean arterial pressures [MAP], central venous pressure [CVP], cardiac index [CI], heart rate [HR], systemic vascular resistance index [SVRI] and/or pulmonary capillary wedge pressure [PCWP]), respiratory (positive end-expiratory pressure [PEEP], peak inspiratory pressure [PIP] and/or ratio of partial pressure arterial oxygen and fraction of inspired oxygen [P/F ratio]), and/or urinary output (UO) following decompressive laparotomy were analyzed.
resultsA total of 15 articles were included; 3 included children only (aged 18 years or younger). Of the 286 patients who were included, 49.7% had primary ACS. The baseline mean IAP in adults decreased with an average of 18.2 ± 6.5 mmHg following decompression, from 31.7 ± 6.4 mmHg to 13.5 ± 3.0 mmHg. There was a decrease in HR (12.2 ± 9.5 beats/min; p = 0.04), CVP (4.6 ± 2.3 mmHg; p = 0.022), PCWP (5.8 ± 2.3 mmHg; p = 0.029), and PIP (10.1 ± 3.9 cmH
conclusionsDecompressive laparotomy resulted in a significantly lower IAP and had beneficial effects on hemodynamic, respiratory, and renal parameters. Mortality after decompressive laparotomy remains high in both adults and children.
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