Evidence map›Paper›PMID 30045713›Full record

ArticleBMC bioinformatics2018

phylotree.js - a JavaScript library for application development and interactive data visualization in phylogenetics.

Stephen D Shank, Steven Weaver, Sergei L Kosakovsky Pond

Abstract read
In one paragraph

Article in BMC bioinformatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Article
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  3. Paralogs of thebioRxiv : the preprint server for biology · 2026
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  19. Evolutionary genomic analyses of canineApplied and environmental microbiology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stephen D ShankDepartment of Biology and Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, 19122, USA. sshank@temple.edu.ORCID 0000-0003-0734-9953
Steven WeaverDepartment of Biology and Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, 19122, USA.
Sergei L Kosakovsky PondDepartment of Biology and Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, 19122, USA.

Funding

Turning big data analysis infrastructure for HIV researchR01AI134384 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI NEKRUTENKO, ANTON, POND, SERGEI L KOSAKOVSKY · 2017 to 2021
$4.2M
Modeling Epidemic Infectious Diseases Using Sequence AnalysisU01GM110749 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI POND, SERGEI L KOSAKOVSKY · 2014 to 2018
$3.0M
HyPhy: Molecular Evolutionary AnalysesR01GM093939 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI MUSE, SPENCER V., POND, SERGEI L KOSAKOVSKY · 2010 to 2018
$2.5M
National Institute of Allergy and Infectious Diseases AI134384NIAID NIH HHS R01 AI134384NIGMS NIH HHS GM093939NIGMS NIH HHS GM110749NIGMS NIH HHS R01 GM093939NIGMS NIH HHS U01 GM110749
6 · The paper itself

Abstract

backgroundWhile several JavaScript packages for visualizing phylogenetic trees exist, most are best characterized as frameworks that are designed with a specific set of tasks in mind. Extending such packages to use cases that are not available as features often ends up being difficult. Moreover, existing packages tend to produce standalone widgets that are not designed to serve as middleware, as opposed to flexible tools that can integrate with other components of an application.

resultsphylotree.js is a library that extends the popular data visualization framework d3.js, and is suitable for building JavaScript applications where users can view and interact with phylogenetic trees. The effects of such interactions can be captured and communicated to other package components, making it possible to engineer complex and responsive applications that include phylogenetic trees. phylotree.js implements several abstractions in addition to features, and comes with a documented application programming interface, thus promoting interoperability and extensibility. Example applications include a tool to visualize and annotate phylogenetic trees, a web application for comparative sequence analysis, a structural viewer that interacts with a large phylogenetic tree, and an interactive tanglegram.

conclusionsphylotree.js is a useful tool and application module for a variety of computational biology software applications. The code is available on Github and is released under the MIT license.

Indexed as

PhylogenySoftwareComputational BiologySequence Analysis, DNAUser-Computer InterfaceD3Data visualizationJavaScriptPhylogenetics

Identifiers

PMID30045713
PMCPMC6060545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.