Evidence map›Paper›PMID 30045257›Full record

ArticleMedicine2018

Fluorescence in situ hybridization microscopic detection of Bacilli Calmette Guérin mycobacteria in aortic lesions: A case report.

Florent Darriet, Paola Bernioles, Ahmed Loukil, Nadia Saidani, Carole Eldin, Michel Drancourt

Abstract readCase Reports
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Leprosy in French Polynesia.New microbes and new infections · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Florent DarrietMicrobiology Laboratory Infectious Disease Department, Assistance Publique -Hôpitaux de Marseille Aix-Marseille University, Institut de Recherche pour le Développement, Microbes, Evolution, Phylogénie, Infections, Institut Hospitalier Universitaire Méditerranée-Infection, Marseille, France.
Paola Bernioles
Ahmed Loukil
Nadia Saidani
Carole Eldin
Michel Drancourt

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleTo improve the diagnosis of life-threatening Bacilli Calmette Guérin (BCG) arterial aneurysm in patients treated by intravesical instillation of BCG vaccine as adjunctive therapy for non-muscular bladder carcinoma, is a life-threatening condition. Its diagnosis remains cumbersome. PATIENT CONCERNS: One patient with a history of intravesical BCG installation presented with aortic aneurysm with routine microscopic examination after Ziehl-Neelsen staining remaining negative. DIAGNOSES: We used fluorescence in situ hybridization (FISH) to target the Mycobacterium tuberculosis complex rpob gene in a fresh aortic specimen. FISH yielded fluorescent mycobacteria in aortic lesions; mycobacteria were further confirmed as Mycobacterium bovis BCG mycobacteria by polymerase chain reaction (PCR) sequencing.

interventionsThe patient benefited from an antituberculous treatment combining rifampicin, isoniazid, and ethambunol. OUTCOME: A 9-month follow-up indicated a favorable outcome. LESSONS: This case report teaches that FISH targeting the M tuberculosis complex rpoB gene should be incorporated in the laboratory investigation of aortic aneurysm in patients with a history of bladder carcinoma.

Indexed as

Aortic Aneurysm, AbdominalBCG VaccineAdjuvants, ImmunologicAdministration, IntravesicalAgedHumansIn Situ Hybridization, FluorescenceMaleMicroscopy, FluorescenceMycobacterium bovisReproducibility of ResultsUrinary Bladder NeoplasmsAdjuvants, ImmunologicBCG Vaccine

Identifiers

PMID30045257
PMCPMC6078740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.