Evidence map›Paper›PMID 30044843›Full record

ArticlePloS one2018

An international multi-centre cohort study of weight loss in overweight cats: Differences in outcome in different geographical locations.

John Flanagan, Thomas Bissot, Marie-Anne Hours, Bernabe Moreno, Alexander J German

Open access · goldAbstract readMulticenter StudyObservational Study, Veterinary
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

John FlanaganRoyal Canin Research Center, Aimargues, France.
Thomas BissotRoyal Canin Research Center, Aimargues, France.
Marie-Anne HoursRoyal Canin Research Center, Aimargues, France.
Bernabe MorenoRoyal Canin Research Center, Aimargues, France.
Alexander J GermanInstitute of Ageing and Chronic Disease, University of Liverpool, Neston, Cheshire, United Kingdom.ORCID 0000-0002-3017-7988
University of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFeline obesity is a worldwide concern which has recently been formally classified as a disease by the veterinary community. Management involves invoking controlled weight loss by feeding a purpose-formulated food in restricted quantities and altering physical activity. Most weight loss studies conducted in cats have been undertaken in research cat colonies from single geographic locations. The aim of this multi-centre cohort study was to determine the efficacy of a short-term dietary weight loss intervention in overweight pet cats across a range of geographical locations globally. MATERIALS AND

methodsA 3-month (median 13 weeks, inter-quartile range [IQR] 12-15 weeks) weight loss programme was conducted at 188 veterinary practices in 22 countries, and involving 730 cats, 413 of which completed the programme and had complete data available. All were fed commercially available dry or wet weight loss diets, and median energy intake was 53 kcal/kg BW0.711/day. The Royal Canin Ethics Committee approved the study, and owners gave informed consent. Owners completed behavioural questionnaires assessing begging, physical activity and quality of life (QOL). Linear mixed models were used to assess the respective influence of time, age, and initial body condition score (BCS) on weight loss and behavioural observations.

resultsAt baseline, median age was 72 months (range 12-200 months) and median BCS was 8 (range 7-9). In all, 402/413 cats (97%) lost weight (mean 10.6±6.3%) during the programme at a rate of 0.8 ±0.50%/week. Based upon owner questionnaires, activity and QOL improved (both P<0.001), while begging behaviour decreased (P<0.001) during weight loss. The main factor influencing percentage weight loss was geographical location (P<0.001), with cats in North America losing less weight (median 7.2%, IQR: 4.4-10.4%) than those in both Europe (10.7%, 6-8-15.4%) and South America (10.0%, 6.2-15.4%). Differences in weight loss were also observed amongst countries (P<0.001), with cats in Argentina, Germany, and Italy losing more weight than cats in the USA, and cats in Germany also losing more weight than cats in Portugal. DISCUSSION/

conclusionMost of the overweight cats enrolled in this international multi-centre study successfully lost weight. The reason for the differences in percentage weight loss amongst geographical locations requires further study.

Indexed as

Diet, ReducingWeight LossAnimalsBehavior, AnimalCat DiseasesCatsFeeding BehaviorFemaleInternationalityMaleMotor ActivityOverweightProspective StudiesQuality of LifeTreatment Outcome

Identifiers

PMID30044843
PMCPMC6059437
OpenAlexW2884558192

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.