ArticlePLoS biology2018
Blindsight relies on a functional connection between hMT+ and the lateral geniculate nucleus, not the pulvinar.
Article in PLoS biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Generalisation of training-induced recovery in occipital stroke: neurochemical and fMRI correlates.bioRxiv : the preprint server for biology · 2026Article
- Distinct temporal dynamics of judging scene-relative object motion and estimating heading from optic flow.Journal of vision · 2025Article
- What V1 Damage Can Teach Us About Visual Perception and Learning.Annual review of vision science · 2025Review
- Rapid degeneration and neurochemical plasticity of the lateral geniculate nucleus following lesions of the primary visual cortex in marmoset monkeys.Current research in neurobiology · 2025Article
- Pathways Mediating Blindsight After V1 Injury: A Systematic Review of Human and Monkey Studies.Basic and clinical neuroscience · 2025Review
- Voxel-Based Lesion-Symptom Mapping Localizes Residual Visual Function in Hemianopia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- On the bright side of blindsight. Considerations from new observations of awareness in a blindsight patient.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Human subcortical pathways automatically detect collision trajectory without attention and awareness.PLoS biology · 2024Article
- Preserved motion perception and the density of cortical projections to V5 in homonymous hemianopia.Brain communications · 2024Article
- Rehabilitating homonymous visual field deficits: white matter markers of recovery-stage 1 registered report.Brain communications · 2024Article
- Rehabilitating homonymous visual field deficits: white matter markers of recovery-stage 2 registered report.Brain communications · 2024Article
- Convolutional neural networks for vision neuroscience: significance, developments, and outstanding issues.Frontiers in computational neuroscience · 2023Review
- A theory of consciousness from a theoretical computer science perspective: Insights from the Conscious Turing Machine.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Neural Mechanisms of Visual Field Recovery after Perceptual Training in Cortical Blindness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Network Localization of Unconscious Visual Perception in Blindsight.Annals of neurology · 2022Article
- Remodeling of lateral geniculate nucleus projections to extrastriate area MT following long-term lesions of striate cortex.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Phylogenetic view of the compensatory mechanisms in motor and sensory systems after neuronal injury.Current research in neurobiology · 2022Review
- The nature of blindsight: implications for current theories of consciousness.Neuroscience of consciousness · 2022Review
- Cortical Visual Impairment in Childhood: 'Blindsight' and the Sprague Effect Revisited.Brain sciences · 2021Review
- An Audiovisual 3D-Immersive Stimulation Program in Hemianopia Using a Connected Device.The American journal of case reports · 2021Article
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2 authors.
Funding
Abstract
When the primary visual cortex (V1) is damaged, the principal visual pathway is lost, causing a loss of vision in the opposite visual field. While conscious vision is impaired, patients can still respond to certain images; this is known as 'blindsight'. Recently, a direct anatomical connection between the lateral geniculate nucleus (LGN) and human motion area hMT+ has been implicated in blindsight. However, a functional connection between these structures has not been demonstrated. We quantified functional MRI responses to motion in 14 patients with unilateral V1 damage (with and without blindsight). Patients with blindsight showed significant activity and a preserved sensitivity to speed in motion area hMT+, which was absent in patients without blindsight. We then compared functional connectivity between motion area hMT+ and a number of structures implicated in blindsight, including the ventral pulvinar. Only patients with blindsight showed an intact functional connection with the LGN but not the other structures, supporting a specific functional role for the LGN in blindsight.
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