Evidence map›Paper›PMID 30044661›Full record

ArticleAmerican journal of physiology. Cell physiology2018

Support of bone mineral deposition by regulation of pH.

Harry C Blair, Quitterie C Larrouture, Irina L Tourkova, Li Liu, Jing Hao Bian, Donna Beer Stolz, Deborah J Nelson, Paul H Schlesinger

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. CFTR mediates ClNature communications · 2026
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  14. An otopetrin family proton channel promotes cellular acid efflux critical for biomineralization in a marine calcifier.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Harry C BlairVeterans Affairs Medical Center , Pittsburgh, Pennsylvania.
Quitterie C LarroutureDepartment of Pathology, University of Pittsburgh , Pittsburgh, Pennsylvania.
Irina L TourkovaDepartment of Pathology, University of Pittsburgh , Pittsburgh, Pennsylvania.
Li LiuDepartment of Pathology, University of Pittsburgh , Pittsburgh, Pennsylvania.
Jing Hao BianDepartment of Pathology, University of Pittsburgh , Pittsburgh, Pennsylvania.
Donna Beer StolzDepartment of Cell Biology, University of Pittsburgh , Pittsburgh, Pennsylvania.
Deborah J NelsonDepartment of Neurobiology, Pharmacology, and Physiology, University of Chicago , Chicago, Illinois.
Paul H SchlesingerDepartment of Cell Biology, Washington University , St. Louis, Missouri.
University of Pittsburgh · USUniversity of Chicago · USVeterans Health Administration · USWashington University in St. Louis · US

Funding

Phagosomal Ion Channels as Therapeutic TargetsR01HL125076 · NHLBI · UNIVERSITY OF CHICAGO · PI NELSON, DEBORAH J. · 2015 to 2022
$5.0M
Regulation of Osteoclastogenesis by CalciumR01AR065407 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BLAIR, HARRY COLBERT, ROBINSON, LISA J · 2013 to 2017
$1.6M
BLRD VA I01 BX002490NHLBI NIH HHS R01 HL125076NIAMS NIH HHS R01 AR065407
6 · The paper itself

Abstract

Osteoblasts secrete collagen and isolate bone matrix from extracellular space. In the matrix, alkaline phosphatase generates phosphate that combines with calcium to form mineral, liberating 8 H

Indexed as

Adenosine TriphosphateAlkaline PhosphataseBone MatrixCalcification, PhysiologicCalciumCell DifferentiationCell MembraneChloride ChannelsCollagen Type IDurapatiteHumansHydrogen-Ion ConcentrationIon TransportLevamisoleMesenchymal Stem CellsOsteoblastsAdenosine TriphosphateAlkaline PhosphataseCalciumChloride ChannelsClC-3 channelCLC-5 chloride channelCollagen Type IDurapatiteLevamisolePhosphatesSlc9a1 protein, mouseSodiumSodium-Hydrogen Exchanger 1Vacuolar Proton-Translocating ATPaseschloride-hydrogen antiporthydroxyapatite depositionsodium-hydrogen exchangevacuolar H+-ATPase

Identifiers

PMID30044661
PMCPMC6230682
OpenAlexW2884710151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.