Evidence map›Paper›PMID 30044440›Full record

ArticleInternational journal of molecular sciences2018

Translocator Protein (TSPO) as a Potential Biomarker in Human Cancers.

Nimisha H Bhoola, Zukile Mbita, Rodney Hull, Zodwa Dlamini

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 77 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Nimisha H BhoolaFaculty of Health Sciences, University of the Witwatersrand, Johannesburg 2193, South Africa. nimisha.bhoola@wits.ac.za.
Zukile MbitaDepartment of Biochemistry, Microbiology and Biotechnology, University of Limpopo, Private Bag X1106, Sovenga 0727, South Africa. Zukile.Mbita@ul.ac.za.
Rodney HullResearch, Innovation & Engagements Portfolio, Mangosuthu University of Technology, Durban 4031, South Africa. rodneyhull@gmail.com.
Zodwa DlaminiResearch, Innovation & Engagements Portfolio, Mangosuthu University of Technology, Durban 4031, South Africa. zodwa.dlamini@mut.ac.za.
Mangosuthu University of Technology · ZAUniversity of Limpopo · ZAUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TSPO is a receptor involved in the regulation of cellular proliferation, apoptosis and mitochondrial functions. Previous studies showed that the expression of TSPO protein correlated positively with tumour malignancy and negatively with patient survival. The aim of this study was to determine the transcription of

Indexed as

A549 CellsAnalysis of VarianceApoptosisBiomarkers, TumorCell ProliferationFemaleHEK293 CellsHeLa CellsHep G2 CellsHumansLigandsMaleNeoplasmsReceptors, GABARNA, MessengerBiomarkers, TumorLigandsReceptors, GABARNA, MessengerTSPO protein, humanbrain cancerbreast cancercolon cancerkidney cancerliver cancerlung cancerprostate cancerstomach cancerTspo

Identifiers

PMID30044440
PMCPMC6121633
OpenAlexW2884461680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.