Evidence map›Paper›PMID 30044434›Full record

ArticleInternational journal of molecular sciences2018

Inherited and Acquired Decrease in Complement Receptor 1 (CR1) Density on Red Blood Cells Associated with High Levels of Soluble CR1 in Alzheimer's Disease.

Rachid Mahmoudi, Sarah Feldman, Aymric Kisserli, Valérie Duret, Thierry Tabary, Laurie-Anne Bertholon, Sarah Badr, Vignon Nonnonhou, Aude Cesar, Antoine Neuraz and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01565434 (Erythrocyte Complement Receptor 1 and Alzheimer Disease), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01565434 nacompletednot on this map

Erythrocyte Complement Receptor 1 and Alzheimer Disease

TypeinterventionalSponsorCHU de ReimsRan2012 to 2015Enrolled200ConditionsAlzheimer DiseaseArmsCR1 impact
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Complement dysregulation and Alzheimer's disease in Down syndrome.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Rachid MahmoudiDepartment of Internal Medicine and Geriatrics, Reims University Hospitals, Maison Blanche Hospital, 45 rue cognac Jay, 51092 Reims, France. rmahmoudi@chu-reims.fr.ORCID 0000-0003-4741-1934
Sarah FeldmanInstitut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche des Cordeliers, UMR 1138 Equipe 22, Paris Descartes, Sorbonne Paris Cité University, 75006 Paris, France. sarah.feldman@aphp.fr.
Aymric KisserliDepartment of Immunology, Reims University Hospitals, Robert Debré Hospital, 51092 Reims, France. akisserli@chu-reims.fr.
Valérie DuretDepartment of Immunology, Reims University Hospitals, Robert Debré Hospital, 51092 Reims, France. vduret@chu-reims.fr.
Thierry TabaryDepartment of Immunology, Reims University Hospitals, Robert Debré Hospital, 51092 Reims, France. ttabary@chu-reims.fr.
Laurie-Anne BertholonDepartment of Internal Medicine and Geriatrics, Reims University Hospitals, Maison Blanche Hospital, 45 rue cognac Jay, 51092 Reims, France. labertholon@chu-reims.fr.
Sarah BadrDepartment of Internal Medicine and Geriatrics, Reims University Hospitals, Maison Blanche Hospital, 45 rue cognac Jay, 51092 Reims, France. sbadr@chu-reims.fr.
Vignon NonnonhouDepartment of Internal Medicine and Geriatrics, Reims University Hospitals, Maison Blanche Hospital, 45 rue cognac Jay, 51092 Reims, France. vnonnonhou@chu-reims.fr.
Aude CesarDepartment of Research and Innovation, Reims University Hospitals, Robert Debré Hospital, 51092 Reims, France. acesar@chu-reims.fr.
Antoine NeurazInstitut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche des Cordeliers, UMR 1138 Equipe 22, Paris Descartes, Sorbonne Paris Cité University, 75006 Paris, France. antoine.neuraz@aphp.fr.ORCID 0000-0001-7142-6728
Jean Luc NovellaDepartment of Internal Medicine and Geriatrics, Reims University Hospitals, Maison Blanche Hospital, 45 rue cognac Jay, 51092 Reims, France. jlnovella@chu-reims.fr.ORCID 0000-0002-7074-7500
Jacques Henri Max CohenDepartment of Immunology, Reims University Hospitals, Robert Debré Hospital, 51092 Reims, France. jhmcohen@gmail.com.
Centre Hospitalier Universitaire de Reims · FRHôpital Necker-Enfants Malades · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complement receptor 1 (

Indexed as

AgedAged, 80 and overAllelesAlzheimer DiseaseBinding SitesCohort StudiesErythrocytesFemaleGenotypeHumansMaleMethylationMultivariate AnalysisPlaque, AmyloidPolymorphism, Restriction Fragment LengthProtein IsoformsCR1 protein, humanProtein IsoformsReceptors, Complement 3bAlzheimer’s diseasecomplementcomplement C3b/C4b receptorcomplement receptor 1CR1 densityCR1 length polymorphismdementiagenetic riskmolecular biologyneurosciences

Identifiers

PMID30044434
PMCPMC6121509
OpenAlexW2882970870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.