Evidence map›Paper›PMID 30044392›Full record

ArticleBiosensors2018

Label-Free Monitoring of Human IgG/Anti-IgG Recognition Using Bloch Surface Waves on 1D Photonic Crystals.

Alberto Sinibaldi, Agostino Occhicone, Peter Munzert, Norbert Danz, Frank Sonntag, Francesco Michelotti

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Fluorophore Coupling to Internal Modes of Bragg Gratings.The journal of physical chemistry. C, Nanomaterials and interfaces · 2020
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Alberto SinibaldiDepartment of Basic and Applied Science for Engineering SBAI, Sapienza University of Rome, 00161 Rome, Italy. alberto.sinibaldi@uniroma1.it.
Agostino OcchiconeDepartment of Basic and Applied Science for Engineering SBAI, Sapienza University of Rome, 00161 Rome, Italy. agostino.occhicone@uniroma1.it.
Peter MunzertFraunhofer Institute for Applied Optics and Precision Engineering IOF, Albert-Einstein-Str. 7, 07745 Jena, Germany. peter.munzert@iof.fraunhofer.de.
Norbert DanzFraunhofer Institute for Applied Optics and Precision Engineering IOF, Albert-Einstein-Str. 7, 07745 Jena, Germany. norbert.danz@iof.fraunhofer.de.
Frank SonntagFraunhofer Institute for Material and Beam Technology IWS, Winterbergstr. 28, 01277 Dresden, Germany. frank.sonntag@iws.fraunhofer.de.ORCID 0000-0002-5850-2199
Francesco MichelottiDepartment of Basic and Applied Science for Engineering SBAI, Sapienza University of Rome, 00161 Rome, Italy. francesco.michelotti@uniroma1.it.
Sapienza University of Rome · ITFraunhofer Institute for Applied Optics and Precision Engineering · DEFraunhofer Institute for Material and Beam Technology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical biosensors based on one-dimensional photonic crystals sustaining Bloch surface waves are proposed to study antibody interactions and perform affinity studies. The presented approach utilizes two types of different antibodies anchored at the sensitive area of a photonic crystal-based biosensor. Such a strategy allows for creating two or more on-chip regions with different biochemical features as well as studying the binding kinetics of biomolecules in real time. In particular, the proposed detection system shows an estimated limit of detection for the target antibody (anti-human IgG) smaller than 0.19 nM (28 ng/mL), corresponding to a minimum surface mass coverage of 10.3 ng/cm². Moreover, from the binding curves we successfully derived the equilibrium association and dissociation constants (K

Indexed as

PhotonsAntibodiesBiosensing TechniquesHumansImmunoglobulin GNanostructuresOptics and PhotonicsAntibodiesImmunoglobulin GBloch surface waveshuman IgG screeningone-dimensional photonic crystalsoptical biosensors

Identifiers

PMID30044392
PMCPMC6163225
OpenAlexW2884947361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.