ArticleeLife2018
Quantification of anti-parasite and anti-disease immunity to malaria as a function of age and exposure.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
100 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Burden of malaria infection among most vulnerable populations in Ethiopia: an umbrella review of systematic reviews and meta-analyses.BMC infectious diseases · 2025Pooled it
- Parasitaemia and fever in uncomplicated Plasmodium vivax malaria: A systematic review and individual patient data meta-analysis.PLoS neglected tropical diseases · 2025Pooled it
- Global patterns of submicroscopicThe Lancet. Microbe · 2021Pooled it
- High value of rapid diagnostic tests to diagnose malaria within children: A systematic review and meta-analysis.Journal of global health · 2020Pooled it
- Trial
- Assessing the Effect of Malaria Exposure History on Tetanus Antibody Waning Rates Among Children in Jinja and Tororo Districts, Uganda.The Journal of infectious diseases · 2026Article
- Article
- CXCR6+ CD127- Tr1 cells balance immunity and persistence in Plasmodium falciparum infection.The Journal of clinical investigation · 2026Article
- Malaria prevalence and epidemiological characteristics in Northern Malawi: a nine-year retrospective hospital-based study.Malaria journal · 2026Article
- Circulating T-follicular helper and type I regulatory T cells have overlapping phenotypes inbioRxiv : the preprint server for biology · 2026Article
- Pediatric malaria in a non-endemic European setting: clinical patterns, laboratory markers, and the ambiguous role of immunity.Infection · 2026Article
- The N-terminal region of malaria vaccine candidate asparagine-rich merozoite antigen is immunodominant and targeted by polyreactive antibodies.Disease models & mechanisms · 2026Article
- Estimating malaria attributable fraction using quantitative PCR in a longitudinal cohort in Eastern Uganda.medRxiv : the preprint server for health sciences · 2026Article
- Age is an intrinsic driver of inflammatory responses to malaria.Nature communications · 2025Article
- CXCR6bioRxiv : the preprint server for biology · 2025Article
- Relating household entomological measures to individual malaria risk.Malaria journal · 2025Article
- Mathematical modeling of malaria vaccination with seasonality and immune feedback.PLoS computational biology · 2025Article
- Stable Plasmodium falciparum merozoite surface protein-1 allelic diversity despite decreasing parasitaemia in children with multiple malaria infections.Malaria journal · 2025Article
- Malaria.The New England journal of medicine · 2025Review
- Prevalence and drivers of malaria infection among asymptomatic and symptomatic community members in five regions with varying transmission intensity in mainland Tanzania.Parasites & vectors · 2025Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
Fundamental gaps remain in our understanding of how immunity to malaria develops. We used detailed clinical and entomological data from parallel cohort studies conducted across the malaria transmission spectrum in Uganda to quantify the development of immunity against symptomatic
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.