Evidence map›Paper›PMID 30044059›Full record

ArticleJournal of the International AIDS Society2018

Expert consensus statement on the science of HIV in the context of criminal law.

Françoise Barré-Sinoussi, Salim S Abdool Karim, Jan Albert, Linda-Gail Bekker, Chris Beyrer, Pedro Cahn, Alexandra Calmy, Beatriz Grinsztejn, Andrew Grulich, Adeeba Kamarulzaman and 10 more

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in Journal of the International AIDS Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
41.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 111 citations in OpenAlex.

  1. Canadian guideline on HIV pre- and postexposure prophylaxis: 2025 update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  2. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  3. Risk of sexual transmission of human immunodeficiency virus with antiretroviral therapy, suppressed viral load and condom use: a systematic review.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2018
    Pooled it
  4. Article
  5. Article
  6. Proteomic Characterization of HIV Infection.Advances in experimental medicine and biology · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Action needed to address molecular HIV surveillance ethical concerns.Canadian journal of public health = Revue canadienne de sante publique · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. It's time to end HIV criminalization.Canadian journal of public health = Revue canadienne de sante publique · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 19 institutions in 18 countries.

Françoise Barré-SinoussiPasteur Institute, Paris, France.
Salim S Abdool KarimMailman School of Public Health, Columbia University, New York, NY, USA.
Jan AlbertDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Linda-Gail BekkerInstitute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
Chris BeyrerDepartment of Epidemiology, Center for AIDS Research and Center for Public Health and Human Rights, John Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Pedro CahnInfectious Diseases Unit, Juan A. Fernandez Hospital Buenos Aires, CABA, Argentina.
Alexandra CalmyInfectious Diseases, Geneva University Hospital, Geneva, Switzerland.ORCID 0000-0002-1137-6826
Beatriz GrinsztejnInstituto Nacional de Infectologia Evandro Chagas-Fiocruz, Fiocruz, Rio de Janeiro, Brazil.
Andrew GrulichKirby Institute, University of New South Wales, Sydney, NSW, Australia.
Adeeba KamarulzamanFaculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Nagalingeswaran KumarasamyYRGCARE Medical Centre, Voluntary Health Services, Chennai, India.
Mona R LoutfyWomen's College Research Institute, Toronto, Canada.
Kamal M El FilaliInfectious Diseases Unit, Ibn Rochd Universtiy Hospital, Casablanca, Morocco.
Souleymane MboupInstitut de Recherche en Santé, de Surveillance Epidemiologique et de Formations, Dakar, Senegal.
Julio Sg MontanerFaculty of Medicine, University of British Columbia, Vancouver, Canada.
Paula MunderiInternational Association of Providers of AIDS Care, Kampala, Uganda.
Vadim PokrovskyRussian Peoples' Friendship University (RUDN- University), Moscow, Russian Federation.
Anne-Mieke VandammeKU Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Clinical and Epidemiological Virology, Leuven, Belgium.
Benjamin YoungInternational Association of Providers of AIDS Care, Washington, DC, USA.
Peter Godfrey-FaussettUNAIDS, Geneva, Switzerland.
Association of Nurses in AIDS Care · USCentre Hospitalier Universitaire Ibn Rochd · MACornell University · USHospital Fernández · ARInstitute of Health Research, Epidemiological Surveillance and Training · SNInstituto Evandro Chagas · BRInstitut Pasteur · FRJohns Hopkins University · USJoint United Nations Programme on HIV/AIDS · CHKarolinska Institutet · SEPeoples' Friendship University of Russia · RURega Institute for Medical Research · BEUniversity Hospital of Geneva · CHUniversity of British Columbia · CAUniversity of Cape Town · ZAUniversity of Malaya · MYUniversity of Toronto · CAUNSW Sydney · AUVoluntary Health Services Hospital · IN

Funding

The FIOCRUZ Therapeutic and Prevention HIV/AIDS Clinical Trials Unit (FioTrials)UM1AI069476 · NIAID · FUNDACAO OSWALDO CRUZ · PI BEATRIZ GRINSZTEJN · 2012 to 2026
$26.3M
NIAID NIH HHS UM1 AI069476
6 · The paper itself

Abstract

introductionGlobally, prosecutions for non-disclosure, exposure or transmission of HIV frequently relate to sexual activity, biting, or spitting. This includes instances in which no harm was intended, HIV transmission did not occur, and HIV transmission was extremely unlikely or not possible. This suggests prosecutions are not always guided by the best available scientific and medical evidence. DISCUSSION: Twenty scientists from regions across the world developed this Expert Consensus Statement to address the use of HIV science by the criminal justice system. A detailed analysis of the best available scientific and medical research data on HIV transmission, treatment effectiveness and forensic phylogenetic evidence was performed and described so it may be better understood in criminal law contexts. Description of the possibility of HIV transmission was limited to acts most often at issue in criminal cases. The possibility of HIV transmission during a single, specific act was positioned along a continuum of risk, noting that the possibility of HIV transmission varies according to a range of intersecting factors including viral load, condom use, and other risk reduction practices. Current evidence suggests the possibility of HIV transmission during a single episode of sex, biting or spitting ranges from no possibility to low possibility. Further research considered the positive health impact of modern antiretroviral therapies that have improved the life expectancy of most people living with HIV to a point similar to their HIV-negative counterparts, transforming HIV infection into a chronic, manageable health condition. Lastly, consideration of the use of scientific evidence in court found that phylogenetic analysis alone cannot prove beyond reasonable doubt that one person infected another although it can be used to exonerate a defendant.

conclusionsThe application of up-to-date scientific evidence in criminal cases has the potential to limit unjust prosecutions and convictions. The authors recommend that caution be exercised when considering prosecution, and encourage governments and those working in legal and judicial systems to pay close attention to the significant advances in HIV science that have occurred over the last three decades to ensure current scientific knowledge informs application of the law in cases related to HIV.

Indexed as

Criminal LawConsensusDisease Transmission, InfectiousFemaleHIV InfectionsHumansMalePhylogenySexual BehaviorViral Loadcriminalizationcriminal lawhuman rightslaw and policypolicyprosecutionrisk factors

Identifiers

PMID30044059
PMCPMC6058263
OpenAlexW2883882230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.