ArticleCancer medicine2018
Radiation-associated sarcoma after breast cancer in a nationwide population: Increasing risk of angiosarcoma.
Article in Cancer medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Primary and secondary breast angiosarcoma: single center report and a meta-analysis.Breast cancer research and treatment · 2019Pooled it
- Complete remission in a rare pelvic angiosarcoma with liposomal doxorubicin: A comprehensive case report and review of literature.Rare tumors · 2025Article
- Radiation-Associated Angiosarcoma of the Breast: The State of the Art of a Rare and Aggressive Disease.Journal of personalized medicine · 2024Review
- Clinicopathologic and molecular correlates to neoadjuvant chemotherapy-induced pathologic response in breast angiosarcoma.Genes, chromosomes & cancer · 2024Article
- Risk Stratification with Sarculator and MSKCC in Patients with Primary and Secondary Angiosarcoma.Life (Basel, Switzerland) · 2024Article
- Primary Cardiac Intimal Sarcoma: Multi-Layered Strategy and Core Role ofDiagnostics (Basel, Switzerland) · 2024Review
- A Radiation Induced Low-Grade Myofibroblastic Sarcoma in the Retropectoral Area After Breast Conserving Surgery: A Case Report.Journal of breast cancer · 2023Article
- Incidence of radiation-associated sarcoma after breast-conserving surgery plus radiation.Journal of surgical oncology · 2023Article
- Risk of Secondary Cancer after Adjuvant Tamoxifen Treatment for Ductal Carcinoma In Situ: A Nationwide Cohort Study in South Korea.Diagnostics (Basel, Switzerland) · 2023Article
- Family cancer history and smoking habit associated with sarcoma in a Japanese population study.Scientific reports · 2022Article
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- The accuracy and dosimetric analysis of 3D-printing non-coplanar template-assisted iodine-125 seed implantation for recurrent chest wall cancer.Journal of contemporary brachytherapy · 2021Article
- Review
- Tumors associated with radiotherapy: a case series.Journal of medical case reports · 2020Article
- Sarcoma of the breast: breast cancer history as etiologic and prognostic factor-A population-based case-control study.Breast cancer research and treatment · 2020Article
- Postoperative radiotherapy-induced leiomyosarcoma in breast cancer: a case report and literature review.Breast cancer (Tokyo, Japan) · 2020Review
- Radiation-associated sarcoma after breast cancer in a nationwide population: Increasing risk of angiosarcoma.Cancer medicine · 2018Article
- A Case Report of Post-RadiotherapyCase reports in oncologyArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radiation-associated sarcoma (RAS) is a rare complication of radiation therapy (RT) to breast cancer (BC). This study explored RAS after RT to BC in a nationwide population-based material. The Finnish Cancer Registry was queried for patients with BC treated during 1953-2014 who were later diagnosed with a secondary sarcoma in 1953-2014. Registry data, patient files, and sarcoma specimens were analyzed to confirm diagnosis and location of RAS at or close to the RT target volume. A total of 132 512 patients were diagnosed with invasive BC during the study period. A subsequent sarcoma was diagnosed in 355 patients. After exclusion, 96 RAS were identified. Angiosarcoma (AS) was the most prevalent histology in 50 (52%) of 96 patients. However, the first radiation-associated AS was diagnosed in a patient treated for BC with breast-conserving surgery in 1984, and thereafter, the proportion of AS continuously increased. The 5-year sarcoma-specific survival was 75.1% for RAS treated with a curative intent. The distribution of histologic subtypes of RAS has changed during the 60 years of this registry study. The first radiation-associated AS was diagnosed in 1989, and presently, AS is the most common histologic subtype of RAS. It is possible that changes in BC treatment strategies are influencing the characteristics of RAS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.