ArticleMemorias do Instituto Oswaldo Cruz2018
Comorbidities increase in-hospital mortality in dengue patients in Brazil.
Article in Memorias do Instituto Oswaldo Cruz, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diabetes mellitus as a risk factor for severe dengue fever and West Nile fever: A meta-analysis.PLoS neglected tropical diseases · 2024Pooled it
- Dengue Virus Infection and Associated Risk Factors in Africa: A Systematic Review and Meta-Analysis.Viruses · 2021Pooled it
- Metabolic and cardiovascular comorbidities as predictors of severe dengue in Vietnamese adults: a retrospective study, 2022-2024.Osong public health and research perspectives · 2026Article
- Dengue Incidence, Seroprevalence, and Expansion Factors from Active Surveillance, Brazil, 2016-2021.Emerging infectious diseases · 2026Article
- Risk factors associated with dengue lethality: case-control study, Joinville, Brazil.Revista da Sociedade Brasileira de Medicina Tropical · 2026Article
- Ambient temperature and dengue hospitalization in Brazil: A 10-year period case time series analysis.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Risk factors for dengue mortality: a 7-year retrospective cohort in Honduras.BMC infectious diseases · 2025Article
- Clinical Characteristics and Outcomes Among Travelers With Severe Dengue : A GeoSentinel Analysis.Annals of internal medicine · 2023Article
- Development and Utility of Practical Indicators of Critical Outcomes in Dengue Patients Presenting to Hospital: A Retrospective Cross-Sectional Study.Tropical medicine and infectious disease · 2023Article
- Moderation effects of serotype on dengue severity across pregnancy status in Mexico.BMC infectious diseases · 2023Article
- [Association between schooling and mortality rate from dengue in Brazil].Cadernos de saude publica · 2023Article
- The association between diabetes and obesity with Dengue infections.Diabetology & metabolic syndrome · 2022Review
- An Overview of Neglected Orthobunyaviruses in Brazil.Viruses · 2022Review
- Article
- Hospital admissions with influenza and impact of age and comorbidities on severe clinical outcomes in Brazil and Mexico.PloS one · 2022Article
- Dengue and Chikungunya virus co-infection in major metropolitan cities of provinces of Punjab and Khyber Pakhtunkhwa: A multi-center study.PLoS neglected tropical diseases · 2021Article
- Clinical and biochemical parameters of COVID-19 patients with prior or active dengue fever.Acta tropica · 2021Article
- Threading the Pieces Together: Integrative Perspective on SARS-CoV-2.Pathogens (Basel, Switzerland) · 2020Review
- An observational prospective cohort study of the epidemiology of hospitalized patients with acute febrile illness in Indonesia.PLoS neglected tropical diseases · 2020Article
- Preexisting chronic conditions for fatal outcome among SFTS patients: An observational Cohort Study.PLoS neglected tropical diseases · 2019Observational
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue remains an unmet public health burden. We determined risk factors for dengue in-hospital mortality in Brazil. Of 326,380 hospitalised dengue cases in 9-45-year-old individuals, there were 971 deaths. Risk of dying was 11-times higher in the presence of underlying common comorbidities (renal, infectious, pulmonary disease and diabetes), similar to the risk of dying from severe dengue and much higher with the combination. Ensuring access to integrated dengue preventative measures in individuals aged ≥ 9 years including those with comorbidities may help achieve the WHO objective of 50% reduction in mortality and 25% reduction in morbidity due to dengue by 2020.
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