Evidence map›Paper›PMID 30043725›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2018

Outbreak of vancomycin-resistant

Nasstasja Wassilew, Helena Mb Seth-Smith, Eveline Rolli, Yvonne Fietze, Carlo Casanova, Urs Führer, Adrian Egli, Jonas Marschall, Niccolò Buetti

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04172025 (Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04172025 recruitingnot on this mapstarted 2019, after this paper: background citation

Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens

TypeobservationalSponsorUniversity Hospital, Basel, SwitzerlandRan2019 to 2029Enrolled10,000ConditionsMultiresistant Bacterial Pathogens, Virulent Bacterial PathogensArmsAnalysis of Bacterial Genome
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Emergence of vancomycin-resistantEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  4. Spread of the novel vancomycin-resistantEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Observational
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Vancomycin Resistance inMicroorganisms · 2022
    Review
  12. Nosocomial outbreak of vancomycin-resistantEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Antimicrobial resistance and antibiotic consumption in intensive care units, Switzerland, 2009 to 2018.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Nasstasja WassilewDepartment of Infectious Diseases, University Hospital Bern, Bern, Switzerland.
Helena Mb Seth-SmithDivision of Clinical Microbiology, University Hospital Basel, Basel, Switzerland.
Eveline RolliDepartment of Infectious Diseases, University Hospital Bern, Bern, Switzerland.
Yvonne FietzeDepartment of Infectious Diseases, University Hospital Bern, Bern, Switzerland.
Carlo CasanovaInstitute for Infectious Diseases, University of Bern, Bern, Switzerland.
Urs FührerInfectious Diseases Department, Biel Hospital, Biel, Switzerland.
Adrian EgliDivision of Clinical Microbiology, University Hospital Basel, Basel, Switzerland.
Jonas MarschallDepartment of Infectious Diseases, University Hospital Bern, Bern, Switzerland.
Niccolò BuettiDepartment of Infectious Diseases, University Hospital Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A large outbreak of vancomycin-resistant enterococci (VRE) is affecting four hospitals in the Canton of Bern, Switzerland, since December 2017. Of 89 cases identified as carriers, 77 (86.5%) VRE isolates were virtually indistinguishable using whole genome sequencing, and identified as multilocus sequence type (MLST) ST796. This clone, previously only described in Australia and New Zealand, is characterised by rapid spread and the ability to cause bloodstream infections. It requires a multifaceted infection prevention effort.

Indexed as

Disease OutbreaksAdultAnti-Bacterial AgentsCross InfectionElectrophoresis, Gel, Pulsed-FieldEnterococcus faeciumFemaleGram-Positive Bacterial InfectionsHumansMaleMicrobial Sensitivity TestsMiddle AgedMultilocus Sequence TypingSwitzerlandVancomycinVancomycin ResistanceAnti-Bacterial AgentsVancomycinemergent cloneenterococcusoutbreakST796vancomycin-resistant enterococciVREwhole genome sequencing

Identifiers

PMID30043725
PMCPMC6152203

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.