ArticleJournal of cancer research and clinical oncology2018
The impact of different doses of indocyanine green on the sentinel lymph-node mapping in early stage endometrial cancer.
Article in Journal of cancer research and clinical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- ESGO/ESTRO/ESP Guidelines for the management of patients with endometrial carcinoma.Virchows Archiv : an international journal of pathology · 2021Guideline
- Consensus on surgical technique for sentinel lymph node dissection in cervical cancer.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024Article
- Sentinel lymph node mapping in endometrial cancer to reduce surgical morbidity: always, sometimes, or never.Przeglad menopauzalny = Menopause review · 2022Review
- Indocyanine green-guided sentinel lymph node mapping during laparoscopic surgery with vaginal cuff closure but no uterine manipulator for cervical cancer.International journal of clinical oncology · 2022Article
- Sentinel lymph node intraoperative analysis in endometrial cancer.Journal of cancer research and clinical oncology · 2020Article
- Surgical staging in endometrial cancer.Journal of cancer research and clinical oncology · 2019Review
- First Experience with Fluorescence in Pediatric Laparoscopy.European journal of pediatric surgery reports · 2019Article
- Controversies in the Management of Early-stage Serous Endometrial Cancer.In vivo (Athens, Greece)Review
- Sentinel Lymph Nodes in Endometrial Cancer Update 2018.Gynecology and minimally invasive therapyReview
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAim of the study is to evaluate the impact of different doses of indocyanine green (ICG) on the sentinel lymph-node (SLN) mapping in endometrial cancer (EC). MATERIALS AND
methodsA retrospective analysis of EC patients undergoing a laparoscopic SLN mapping at two institutions was performed. Two different injection protocols were used (protocol # 1: 5 mg/ml and a volume of 8 ml; protocol # 2: 1.25 mg/ml and a volume of 4 ml). In every case, the injection was intracervical. The laparoscopic equipment adopted was the same among both institutions. Overall and bilateral detection rates (DR) and median number of retrieved SLNs were calculated. At uni- and multivariate analysis factors (including ICG dose) associated with DR and number of detected SLNs were investigated.
resultsOverall, 168 patients were included. The overall and bilateral DR were 96.3 and 84.5%. Median number of removed SLNs was 3 (0-18). In 56% of the patients, a median number of 6 (1-93) non-SLNs (NSLNs) were removed. Seventeen (10.1%) patients had metastatic SLNs. At multivariate analysis, no factors were associated with bilateral DR. ICG dose was the only factor associated with number of removed SLNs at multivariate analysis.
conclusionA larger dose of ICG is associated with a higher number of retrieved SLNs but not with an increased bilateral DR.
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