Evidence map›Paper›PMID 30043249›Full record

ArticleWiener klinische Wochenschrift2018

Ruxolitinib therapy for myelofibrosis in Austria : Consensus on therapy management.

Maria-Theresa Krauth, Sonja Burgstaller, Veronika Buxhofer-Ausch, Günther Gastl, Klaus Geissler, Felix Keil, Peter Krippl, Thomas Melchardt, Andreas Petzer, Holger Rumpold and 4 more

Erratum issuedOpen access · hybridAbstract readConsensus Statement
In one paragraph

Article in Wiener klinische Wochenschrift, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 1 country.

Maria-Theresa KrauthDepartment of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University Vienna, Vienna, Austria. maria.krauth@meduniwien.ac.at.
Sonja BurgstallerDepartment of Internal Medicine IV, Klinikum Wels-Grieskirchen, Wels, Austria.
Veronika Buxhofer-AuschDepartment of Internal Medicine I, Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Ordensklinikum Linz-Elisabethinen, Linz, Austria.
Günther GastlDepartment of Internal Medicine V, Division Hematology and Oncology, Medical University of Innsbruck, Innsbruck, Austria.
Klaus GeisslerFifth Medical Department, Hospital Hietzing, Vienna, Austria.
Felix KeilThird Medical Department, Hanusch Hospital, Vienna, Austria.
Peter KripplDepartment of Internal Medicine, LKH Fürstenfeld, Krankenhausverbund Feldbach, Fürstenfeld, Austria.
Thomas MelchardtThird Medical Department, Division Hematology and Medical Oncology, Paracelsus Medical University Salzburg, Salzburg, Austria.
Andreas PetzerDepartment of Internal Medicine I, Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Ordensklinikum Linz-Elisabethinen, Linz, Austria.
Holger RumpoldInternal Medicine II, Medical Oncology, Hematology, Gastroenterology and Rheumatology, Academic Teaching Hospital Feldkirch, Feldkirch, Austria.
Thamer SliwaThird Medical Department, Hanusch Hospital, Vienna, Austria.
Stefan WöhrerPermedio Center for Personalized Medicine and Sanatorium Hera Vienna, Vienna, Austria.
Albert WölflerDivision of Hematology, Medical University of Graz, Graz, Austria.
Heinz GisslingerDepartment of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University Vienna, Vienna, Austria.
Hanusch Hospital · ATKrankenhaus der Elisabethinen · ATMedical University of Vienna · ATKlinik Hietzing · ATKlinikum Wels-Grieskirchen · ATLandeskrankenhaus Feldkirch · ATMedical University of Graz · ATParacelsus Medical University · ATUniversität Innsbruck · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral Janus associated kinase (JAK1/2) inhibitor ruxolitinib has been available for treatment of patients with intermediate or high-risk myelofibrosis in Europe since 2012. Since its introduction, the expertise of prescribing doctors with respect to ruxolitinib function, efficacy and adverse effects has consistently been augmented, resulting in therapy modalities that are better tailored to individual patients as well as in increased safety of the treatment. The present consensus on ruxolitinib therapy management has been elaborated by Austrian experts in myeloproliferative neoplasms in line with international treatment guidelines. Our recommendations aim to contribute to an improved management of patients with myelofibrosis treated with ruxolitinib.

Indexed as

Primary MyelofibrosisAustriaEuropeHumansNitrilesPyrazolesPyrimidinesRetrospective StudiesNitrilesPyrazolesPyrimidinesruxolitinibJanus kinase 2Myeloproliferative disordersPost-essential thrombocythemia myelofibrosisPost-polycythemia vera myelofibrosisPrimary myelofibrosis

Identifiers

PMID30043249
PMCPMC6132876
OpenAlexW2882971376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.