Evidence map›Paper›PMID 30043238›Full record

ReviewRheumatology international2018

Prospects of using cardiovascular magnetic resonance in the identification of arrhythmogenic substrate in autoimmune rheumatic diseases.

Sophie I Mavrogeni, Petros P Sfikakis, Theodoros Dimitroulas, Loukia Koutsogeorgopoulou, George Markousis-Mavrogenis, George Poulos, Genovefa Kolovou, George Theodorakis, George D Kitas

Abstract readReview
PubMed Publisher
In one paragraph

Review in Rheumatology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Sophie I MavrogeniOnassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P. Faliro, Athens, Greece. soma13@otenet.gr.
Petros P SfikakisJoint Rheumatology Programme, National and Kapodistrian University of Athens Medical School, Athens, Greece.
Theodoros DimitroulasDepartment of Internal Medicine, Rheumatology, Aristotle University, Thessaloniki, Greece.
Loukia KoutsogeorgopoulouDepartment of Pathophysiology, Laikon Hospital, Athens, Greece.
George Markousis-MavrogenisOnassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P. Faliro, Athens, Greece.
George PoulosOnassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P. Faliro, Athens, Greece.
Genovefa KolovouOnassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P. Faliro, Athens, Greece.
George TheodorakisOnassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P. Faliro, Athens, Greece.
George D KitasArthritis Research UK Epidemiology Unit, University of Manchester, Manchester, UK.
Onassis Cardiac Surgery Center · GRAristotle University of Thessaloniki · GRLaiko General Hospital of Athens · GRNational and Kapodistrian University of Athens · GRVersus Arthritis · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sudden cardiac death (SCD) is due to ventricular tachycardia/fibrillation (VT/VF) and may occur with or without any structural or functional heart disease. The presence of myocardial edema, ischemia and/or fibrosis plays a crucial role in the pathogenesis of VT/VF, irrespective of the pathophysiologic background of the disease. Specifically, in autoimmune rheumatic diseases (ARDs), various entities such as myocardial/vascular inflammation, ischemia and fibrosis may lead to VT/VF. Furthermore, autonomic dysfunction, commonly found in ARDs, may also contribute to SCD in these patients. The only non-invasive, radiation-free imaging modality that can perform functional assessment and tissue characterization is cardiovascular magnetic resonance (CMR). Due to its capability to detect and quantify edema, ischemia and fibrosis in parallel with ventricular function assessment, CMR has the great potential to identify ARD patients at high risk for VT/VF, thus influencing both cardiac and anti-rheumatic treatment and modifying perhaps the criteria for implantation of cardioverter defibrillators.

Indexed as

Death, Sudden, CardiacHumansMagnetic Resonance ImagingRheumatic DiseasesRisk AssessmentRisk FactorsSeverity of Illness IndexTachycardia, VentricularTumor Necrosis Factor-alphaVentricular FibrillationTumor Necrosis Factor-alphaAutoimmune diseasesCardiovascular magnetic resonanceEdemaFibrosisMyocardial infarctionMyocarditisVasculitisVentricular fibrillationVentricular tachycardia

Identifiers

PMID30043238
OpenAlexW2884839240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.