Evidence map›Paper›PMID 30043183›Full record

ArticleEuropean journal of applied physiology2018

Compression socks and the effects on coagulation and fibrinolytic activation during marathon running.

E K Zadow, M J Adams, S S X Wu, C M Kitic, I Singh, A Kundur, N Bost, A N B Johnston, J Crilly, A C Bulmer and 2 more

Abstract read
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In one paragraph

Article in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Black holes in compression therapy: A quest for data.Journal of vascular surgery. Venous and lymphatic disorders · 2024
    Review
  5. Innovation strategy on the example of companies using bamboo.Journal of innovation and entrepreneurship · 2021
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

E K ZadowSchool of Health Sciences, Sports Performance Optimisation Research Team, University of Tasmania, Locked Bag 1322, Newnham, Tasmania, TA, 7250, Australia. Emma.Zadow@utas.edu.au.
M J AdamsSchool of Health Sciences, Sports Performance Optimisation Research Team, University of Tasmania, Locked Bag 1322, Newnham, Tasmania, TA, 7250, Australia.
S S X WuSchool of Health Sciences, Sports Performance Optimisation Research Team, University of Tasmania, Locked Bag 1322, Newnham, Tasmania, TA, 7250, Australia.
C M KiticSchool of Health Sciences, Sports Performance Optimisation Research Team, University of Tasmania, Locked Bag 1322, Newnham, Tasmania, TA, 7250, Australia.
I SinghMenzies Health Institute Queensland and School of Medical Science, Griffith University, Queensland, Australia.
A KundurMenzies Health Institute Queensland and School of Medical Science, Griffith University, Queensland, Australia.
N BostSchool of Nursing and Midwifery and Menzies Health Institute, Queensland, Griffith University, Queensland, Australia.
A N B JohnstonSchool of Nursing and Midwifery and Menzies Health Institute, Queensland, Griffith University, Queensland, Australia.
J CrillySchool of Nursing and Midwifery and Menzies Health Institute, Queensland, Griffith University, Queensland, Australia.
A C BulmerMenzies Health Institute Queensland and School of Medical Science, Griffith University, Queensland, Australia.
S L HalsonDepartment of Physiology, Australian Institute of Sport, Belconnen, Canberra, Australia.
J W FellSchool of Health Sciences, Sports Performance Optimisation Research Team, University of Tasmania, Locked Bag 1322, Newnham, Tasmania, TA, 7250, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCompression socks are frequently used in the treatment and prevention of lower-limb pathologies; however, when combined with endurance-based exercise, the impact of compression socks on haemostatic activation remains unclear.

objectivesTo investigate the effect of wearing compression socks on coagulation and fibrinolysis following a marathon.

methodsSixty-seven participants [43 males (mean ± SD: age: 46.7 ± 10.3 year) and 24 females (age: 40.0 ± 11.0 year)] were allocated into a compression (SOCK, n = 34) or control (CONTROL, n = 33) group. Venous blood samples were obtained 24 h prior to and immediately POST-marathon, and were analyzed for thrombin-anti-thrombin complex (TAT), tissue factor (TF), tissue factor pathway inhibitor (TFPI), and D-Dimer.

resultsCompression significantly attenuated the post-exercise increase in D-Dimer compared to the control group [median (range) SOCK: + 9.02 (- 0.34 to 60.7) ng/mL, CONTROL: + 25.48 (0.95-73.24) ng/mL]. TF increased following the marathon run [median (range), SOCK: + 1.19 (- 7.47 to 9.11) pg/mL, CONTROL: + 3.47 (- 5.01 to 38.56) pg/mL] in all runners. No significant post-exercise changes were observed for TAT and TFPI.

conclusionsWhile activation of coagulation and fibrinolysis was apparent in all runners POST-marathon, wearing compression socks was shown to reduce fibrinolytic activity, as demonstrated by lower D-Dimer concentrations. Compression may reduce exercise-associated haemostatic activation when completing prolonged exercise.

Indexed as

Endurance TrainingFibrinolysisStockings, CompressionAdultFemaleHealthy VolunteersHumansMaleMiddle AgedRunningCompressionD-dimerThrombin–anti-thrombin complexesTissue factorTissue factor pathway inhibitor

Identifiers

PMID30043183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.