ArticleSurgical endoscopy2019
Long-term and short-term surgical outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma: might laparoscopic approach be better in early HCC?
Article in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- An inflammation-nutrition-surgery-based INSEP model and a web-based clinical decision support system for predicting early postoperative infection in elderly patients with hepatocellular carcinoma: a multicenter retrospective study.Frontiers in nutrition · 2026Article
- Feasibility of robotic liver resection compared with laparoscopic and open liver resection for hepatocellular carcinoma: a network meta-analysis.International journal of surgery (London, England) · 2026Article
- Open versus laparoscopic oncologic resection for gallbladder cancer after index cholecystectomy: international multicenter comparative study.Langenbeck's archives of surgery · 2025Article
- Impact of metabolic dysfunction-associated fatty liver disease on the outcomes following laparoscopic hepatectomy for hepatocellular carcinoma.Surgical endoscopy · 2024Article
- Impact of particle size of multivesicular liposomes on the embolic and therapeutic effects in rabbit VX2 liver tumor.Drug delivery · 2023Article
- Comparison of the short-term outcomes of open and laparoscopic hepatectomy in the treatment of recurrent hepatocellular carcinoma: a single-center retrospective study.Translational cancer research · 2022Article
- Laparoscopic isolated liver segmentectomy 8 for malignant tumors: techniques and comparison of surgical results with the open approach using a propensity score-matched study.Langenbeck's archives of surgery · 2022Article
- External validation of different difficulty scoring systems of laparoscopic liver resection for hepatocellular carcinoma.Surgical endoscopy · 2022Article
- Impact of non-liver-related previous abdominal surgery on the difficulty of minimally invasive liver resections: a propensity score-matched controlled study.Surgical endoscopy · 2022Article
- Efficacy and safety of various primary treatment strategies for very early and early hepatocellular carcinoma: a network meta-analysis.Cancer cell international · 2021Review
- Factors affecting sufentanil consumption for intravenous controlled analgesia after hepatectomy: retrospective analysis.BMC anesthesiology · 2021Article
- Long-term survival outcome of laparoscopic liver resection for hepatocellular carcinoma.World journal of gastrointestinal surgery · 2021Article
- Laparoscopic hepatectomy for hepatocellular carcinoma: short- and long-term outcomes with blood loss.Translational cancer research · 2021Article
- Laparoscopic Versus Open Liver Resection for Hepatocellular Carcinoma: A Case Controlled Study with Propensity Score Matching.World journal of surgery · 2021Article
- Laparoscopic Liver Resection Should Be a Standard Procedure for Hepatocellular Carcinoma with Low or Intermediate Difficulty.Journal of personalized medicine · 2021Article
- Is the Barcelona Clinic Liver Cancer guideline for treating intermediate to advanced staged hepatocellular carcinoma still appropriate?Annals of translational medicine · 2021Article
- LaparoscopicFrontiers in oncology · 2021Article
- Laparoscopic versus open left hemihepatectomy for hepatocellular carcinoma: a propensity score matching analysis.Translational cancer research · 2020Article
- The Postoperative Analgesic Effect of Ultrasound-Guided Bilateral Transversus Abdominis Plane Combined with Rectus Sheath Blocks in Laparoscopic Hepatectomy: A Randomized Controlled Study.Therapeutics and clinical risk management · 2020Article
- Analgesic effect of parecoxib combined with ropivacaine in patients undergoing laparoscopic hepatectomy.World journal of clinical cases · 2019Article
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Abstract
backgroundThis retrospective study compared the short- and long-term outcomes of laparoscopic liver resection (LLR) and open liver resection (OLR) and identified patients who might gain more benefits from LLR.
methodsThe demographic and perioperative data, short-term surgical outcomes, and long-term oncological results of all 313 patients who received elective liver resection for hepatocellular carcinoma (HCC) between January 2010 and June 2017 were analyzed. The patients were then divided into stage-specific subgroups according to the TNM staging system for comparison.
resultsLLR was performed in 153 patients and OLR in 160 patients. LLR is associated with less blood loss (p < 0.001), shorter surgical time (p = 0.001), shorter length of hospital stay (p < 0.001), and lower morbidity rate (p = 0.034). The 5-year overall survival (OS) rates in the LLR group were higher than those in the OLR group (78.1 vs. 57.6%; p = 0.002). Stage-specific subgroup analysis revealed similar 5-year OS in the two groups (stage I: 82.8 vs. 82.6%, p = 0.845; stage II: 80.3 vs. 69.2%, p = 0.638; stage III: 55.6 vs. 34.8%, p = 0.681), as did the 5-year recurrence-free survival. Moreover, the short-term outcomes were better in the LLR group in terms of surgical time, blood loss, and length of hospital stay, and these benefits attenuated with advancing tumor stage.
conclusionsLLR for HCC is a safe and feasible procedure that does not compromise long-term oncological outcomes. In early tumor stages, LLR might be better in terms of short-term surgical outcomes.
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