Evidence map›Paper›PMID 30042790›Full record

ArticleNeuro-ophthalmology (Aeolus Press)2018

Invasive Fungal Sinusitis Presenting as Acute Posterior Ischemic Optic Neuropathy.

Rafat Ghabrial, Arjun Ananda, Sebastiaan J van Hal, Elizabeth O Thompson, Stephen R Larsen, Peter Heydon, Ruta Gupta, Svetlana Cherepanoff, Michael Rodriguez, Gabor Michael Halmagyi

Open access · greenAbstract read
In one paragraph

Article in Neuro-ophthalmology (Aeolus Press), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Rafat GhabrialOphthalmology Department, Royal Prince Alfred Hospital, Sydney, Australia.
Arjun AnandaOtorhinolaryngology Department, Royal Prince Alfred Hospital, Sydney, Australia.
Sebastiaan J van HalMicrobiology and Infectious Diseases Department, Royal Prince Alfred Hospital, Sydney, Australia.
Elizabeth O ThompsonRadiology Department, Royal Prince Alfred Hospital, Sydney, Australia.
Stephen R LarsenInstitute of Haematology, Royal Prince Alfred Hospital, Sydney, Australia.
Peter HeydonOphthalmology Department, Royal Prince Alfred Hospital, Sydney, Australia.
Ruta GuptaAnatomical Pathology Department, Royal Prince Alfred Hospital, Sydney, Australia.
Svetlana CherepanoffAnatomical Pathology Department, St Vincent's Hospital, Sydney, Australia.
Michael RodriguezAnatomical Pathology Department, St Vincent's Hospital, Sydney, Australia.
Gabor Michael HalmagyiNeurology Department, Royal Prince Alfred Hospital, Sydney, Australia.
Royal Prince Alfred Hospital · AUSt Vincent's Hospital Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive fungal sinusitis causes painful orbital apex syndrome with ophthalmoplegia and visual loss; the mechanism is unclear. We report an immunocompromised patient with invasive fungal sinusitis in whom the visual loss was due to posterior ischaemic optic neuropathy, shown on diffusion-weighted MRI, presumably from fungal invasion of small meningeal-based arteries at the orbital apex. After intensive antifungal drugs, orbital exenteration and immune reconstitution, the patient survived, but we were uncertain if the exenteration helped. We suggest that evidence of acute posterior ischaemic optic neuropathy should be a contra-indication to the need for orbital exenteration in invasive fungal sinusitis.

Indexed as

Invasive fungal sinusitisorbital exenterationposterior ischaemic optic neuropathy

Identifiers

PMID30042790
PMCPMC6056227
OpenAlexW2768043982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.