Evidence map›Paper›PMID 30042784›Full record

ArticleFrontiers in genetics2018

Role of Signaling Molecules in Mitochondrial Stress Response.

Shauna Hill, Kavithalakshmi Sataranatarajan, Holly Van Remmen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. MOTS-c as a Potential Diagnostic-prognostic Biomarker for Myocardial Infarction.Cardiovascular & hematological agents in medicinal chemistry · 2025
    Article
  6. Mitochondrial Signaling Pathways Associated with DNA Damage Responses.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Review
  9. Review
  10. Lysosomal Stress Response (LSR): Physiological Importance and Pathological Relevance.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Review
  11. Review
  12. Review
  13. Review
  14. Role of the mitochondrial stress response in human cancer progression.Experimental biology and medicine (Maywood, N.J.) · 2020
    Review
  15. Mitonuclear genomics and aging.Human genetics · 2020
    Review
  16. MOTS-c: A Mitochondrial-Encoded Regulator of the Nucleus.BioEssays : news and reviews in molecular, cellular and developmental biology · 2019
    Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shauna HillAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.
Kavithalakshmi SataranatarajanAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.
Holly Van RemmenAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.
Oklahoma Medical Research Foundation · USThe University of Texas at San Antonio · US

Funding

A novel role for mitochondrial dysfunction in mitochondrial signalingF31AG047764 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HILL, SHAUNA · 2014 to 2016
$84k
NIA NIH HHS F31 AG047764
6 · The paper itself

Abstract

Mitochondria are established essential regulators of cellular function and metabolism. Mitochondria regulate redox homeostasis, maintain energy (ATP) production through oxidative phosphorylation, buffer calcium levels, and control cell death through apoptosis. In addition to these critical cell functions, recent evidence supports a signaling role for mitochondria. For example, studies over the past few years have established that peptides released from the mitochondria mediate stress responses such as the mitochondrial unfolded protein response (UPR

Indexed as

longevitymitochondriaretrograde responsesignaling peptidesstress response

Identifiers

PMID30042784
PMCPMC6048194
OpenAlexW2808614921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.