Evidence map›Paper›PMID 30042601›Full record

ArticleReumatologia2018

Satisfaction and discontent of Polish patients with biological therapy of rheumatic diseases: results of a multi-center questionnaire study.

Anna Kotulska, Eugeniusz J Kucharz, Piotr Wiland, Marzena Olesińska, Anna Felis-Giemza, Magdalena Kopeć-Mędrek, Aleksandra Zoń-Giebel, Wojciech Romanowski, Lucyna Szymczak-Bartz, Małgorzata Tłustochowicz and 25 more

Open access · diamondAbstract read
In one paragraph

Article in Reumatologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 9 institutions in 1 country.

Anna KotulskaDepartment of Internal Medicine, Rheumatology and Clinical Immunology, Medical University of Silesia, Katowice, Poland.
Eugeniusz J KucharzDepartment of Internal Medicine, Rheumatology and Clinical Immunology, Medical University of Silesia, Katowice, Poland.
Piotr WilandDepartment of Rheumatology and Internal Medicine, Wrocław Medical University, Wrocław, Poland.
Marzena OlesińskaDepartment and Clinic of Systemic Connective Tissue Diseases, National Institute of Geriatics, Rheumatology and Rehabilitation, Warsaw, Poland.
Anna Felis-GiemzaDepartment and Clinic of Systemic Connective Tissue Diseases, National Institute of Geriatics, Rheumatology and Rehabilitation, Warsaw, Poland.
Magdalena Kopeć-MędrekDepartment of Internal Medicine, Rheumatology and Clinical Immunology, Medical University of Silesia, Katowice, Poland.
Aleksandra Zoń-GiebelGeneral Jerzy Ziętek Silesian Centre of Rheumatology, Rehabilitation and Disability Prevention, Ustroń, Poland.
Wojciech RomanowskiGreater Poland Rheumatological Centre, Śrem, Poland.
Lucyna Szymczak-BartzGreater Poland Rheumatological Centre, Śrem, Poland.
Małgorzata TłustochowiczDepartment of Internal Medicine and Rheumatology, Military Medical Institute, Warsaw, Poland.
Jolanta LewandowiczDivision of Rheumatology, Nicolaus Copernicus Regional Specialist Hospital, Łódź, Poland.
Joanna Kowalska-MajkaDivision of Rheumatology, Nicolaus Copernicus Regional Specialist Hospital, Łódź, Poland.
Jolanta BuckaDivision of Rheumatology, Józef Dietl Specialist Hospital, Krakow, Poland.
Maria MajdanDepartment of Rheumatology and Systemic Connective Tissue Diseases, Medical University of Lublin, Lublin, Poland.
Zofia KiełbikDepartment of Rheumatology and Systemic Connective Tissue Diseases, Medical University of Lublin, Lublin, Poland.
Mariusz KorkoszDivision of Rheumatology, Department of Internal Medicine and Gerontology, Collegium Medicum, Jagiellonian University, Krakow, Poland.
Aneta BielińskaDivision of Rheumatology, Department of Internal Medicine and Gerontology, Collegium Medicum, Jagiellonian University, Krakow, Poland.
Piotr LeszczyńskiDepartment of Rheumatology and Rehabilitation, Poznan University of Medical Sciences, Poznan, and Division of Rheumatology and Osteoporosis, Józef Struś Specialist Municipal Hospital, Poznań, Poland.
Katarzyna Pawlak-BuśDepartment of Rheumatology and Rehabilitation, Poznan University of Medical Sciences, Poznan, and Division of Rheumatology and Osteoporosis, Józef Struś Specialist Municipal Hospital, Poznań, Poland.
Mariusz J PuszczewiczDepartment of Rheumatology and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland.
Dominik MajewskiDepartment of Rheumatology and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland.
Katarzyna SmolikDivision of Rheumatology, Murcki Hospital, Katowice, Poland.
Teresa Migas-KuklaDivision of Rheumatology, Murcki Hospital, Katowice, Poland.
Małgorzata Sochocka-BykowskaDr Jadwiga Titz-Kosko Regional Hospital for Rheumatic Disease, Sopot, Poland.
Maria SzareckaDr Jadwiga Titz-Kosko Regional Hospital for Rheumatic Disease, Sopot, Poland.
Bernadeta LuberdaDr Jadwiga Titz-Kosko Regional Hospital for Rheumatic Disease, Sopot, Poland.
Małgorzata Falenta-HitnarowiczDivision of Rheumatology, Pulmonology and Rheumatology Medical Centre, Kup, Poland.
Jadwiga Świkszcz-GniadekDivision of Rheumatology, Nicolaus Copernicus Municipal Hospital, Olsztyn, Poland.
Wanda Lepiarz-RusekDivision of Rheumatology, St. Barbara Regional Specialist Hospital, Sosnowiec, Poland.
Grzegorz RozwadowskiDivision of Rheumatology, Lower Silesian Rehabilitation Centre, Kamienna Góra, Poland.
Barbara CharaDivision of Rheumatology, Holy Spirit Specialist Hospital, Sandomierz, Poland.
Jerzy ZajdelDivision of Rheumatology, Regional Specialist Hospital, Częstochowa, Poland.
Zbigniew ZdrojewskiDepartment of Internal Medicine, Connective Tissue Diseases and Geriatrics, Medical University of Gdansk, Gdańsk, Poland.
Maria Maciejowska-RogeDivision of Rheumatology, Health Care Centre, Włoszczowa, Poland.
Irena Rosmus-KucziaFirst Division of Rheumatology, Hospital for Rheumatology and Rehabilitation, Goczałkowice Zdrój, Poland.
Poznan University of Medical Sciences · PLMedical University of Silesia · PLJagiellonian University · PLMedical University of Lublin · PLNational Institute of Geriatrics, Rheumatology and Rehabilitation · PLGdańsk Medical University · PLMalopolska Higher Vocational School of J. Dietl in Kraków · PLSilesian Center for Heart Disease · PLWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesBiologics are medications widely applied in the management of inflammatory rheumatic diseases. The drugs were found to be effective but their application is associated with some disadvantages. Medication with biologics is relatively expensive, and in Poland, it is carried out in specialized centers. The study was designed to evaluate various aspects of satisfaction and dissatisfaction of Polish patients treated with biologics. MATERIAL AND

methodsAn anonymous questionnaire was distributed in 23 Polish rheumatological centers involved in the treatment; 1212 returned questionnaires were used for analysis. Responses were received from 606 patients with rheumatoid arthritis, 427 with ankylosing spondylitis, 117 psoriatic arthritis, and 62 adult patients with juvenile idiopathic arthritis (in whom administration of the drugs had been introduced before they were 18 years old). The investigated group constituted about one-fifth of all rheumatic patients on biologics in Poland.

resultsA beneficial or very beneficial influence of the medication on the state of physical health was found mostly in patients with rheumatoid arthritis (51.3 and 30.5%) and ankylosing spondylitis (51.0 and 36.8%). Family life was improved by the treatment especially in patients with ankylosing spondylitis (40.7 and 35.6% beneficial and very beneficial, respectively), sleep quality and sexual life mostly in those with ankylosing spondylitis (beneficial/very beneficial influence 41.5/38.4, and 38.7/23.9, respectively). There was a rather small influence of biological treatment on the financial situation of the patients. In general, satisfaction with the treatment was evaluated as positive or very positive in 88% of all investigated patients.In a significant part of the patients, transportation to the medical center was considered as a disadvantage of the treatment. About one-third of the patients considered laboratory and imaging tests to be done before initiation of the medication as a difficulty, and for about 40% waiting time for qualification for the medication was a significant disadvantage. The route of drug administration was without importance for 4/5 of the patients.

conclusionsSumming up, the results were similar in the patients suffering from various diseases although those with psoriatic arthritis felt the highest satisfaction (possibly due to the positive aesthetic effect), and those with ankylosing spondylitis had significant improvement in sexual life (probably due to younger age). Relatively low satisfaction was found in patients with juvenile idiopathic arthritis. There was a small influence of medication on financial status of the patients. Application of biologics has few disadvantages and most of them are associated with the organization of health services (waiting time for the tests, transportation to the medical centers).

Indexed as

ankylosing spondylitisbiological therapyjuvenile idiopathic arthritispsoriatic arthritisrheumatoid arthritis

Identifiers

PMID30042601
PMCPMC6052366
OpenAlexW2884380963

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.