Trial reportJournal of perinatology : official journal of the California Perinatal Association2018
Effect of a lifestyle intervention during pregnancy-findings from the Finnish gestational diabetes prevention trial (RADIEL).
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Systematic review of interventions in early pregnancy among pregnant individuals at risk for hyperglycemia.American journal of obstetrics & gynecology MFM · 2025Pooled it
- Effective dietary interventions during pregnancy: a systematic review and meta-analysis of behavior change techniques to promote healthy eating.BMC pregnancy and childbirth · 2025Pooled it
- Association of Antenatal Diet and Physical Activity-Based Interventions With Gestational Weight Gain and Pregnancy Outcomes: A Systematic Review and Meta-analysis.JAMA internal medicine · 2022Pooled it
- Genetic risk of type 2 diabetes modifies the effects of a lifestyle intervention aimed at the prevention of gestational and postpartum diabetes.Diabetologia · 2022Trial
- Preconception lifestyle intervention in women with obesity and echocardiographic indices of cardiovascular health in their children.International journal of obesity (2005) · 2022Trial
- Trial
- Lifestyle Intervention for Overweight/Obese Pregnant Women with Polycystic Ovarian Syndrome: Lessons and Challenges.Obesity facts · 2021Trial
- Effects of maternal lifestyle interventions on child neurobehavioral development: Follow-up of randomized controlled trials.Scandinavian journal of psychology · 2019Trial
- Obesity and Its Role in Fetal Programming-A Narrative Review.Nutrients · 2025Review
- Maternal and Neonatal Efficacy and Safety Outcomes of Myo-Inositol in Women With or at High Risk of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis.Diabetes spectrum : a publication of the American Diabetes Association · 2025Article
- Evaluation of machine learning models for early prediction of gestational diabetes using retrospective electronic health records from current and previous pregnancies.BMJ digital health & AI · 2025Article
- Body Esteem and Self-Efficacy of Pregnant Women with Gestational Diabetes Mellitus.International journal of environmental research and public health · 2023Article
- Programming by maternal obesity: a pathway to poor cardiometabolic health in the offspring.The Proceedings of the Nutrition Society · 2022Review
- Macronutrient intake during pregnancy in women with a history of obesity or gestational diabetes and offspring adiposity at 5 years of age.International journal of obesity (2005) · 2021Article
- Reducing intergenerational obesity and diabetes risk.Diabetologia · 2021Review
- Maternal Obesity: A Focus on Maternal Interventions to Improve Health of Offspring.Frontiers in cardiovascular medicine · 2021Review
- Maternal Obesity and Diabetes Mellitus as Risk Factors for Congenital Heart Disease in the Offspring.Journal of the American Heart Association · 2020Review
- Observational
- Most Women with Previous Gestational Diabetes Mellitus Have Impaired Glucose Metabolism after a Decade.International journal of molecular sciences · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the effect of lifestyle counseling on perinatal outcomes among women at high risk for gestational diabetes. STUDY
designA total of 492 women with obesity and/or prior gestational diabetes were allocated to intervention (four sessions of lifestyle counseling, n = 249) or usual care (n = 243) before 20 weeks' gestation.
resultLifestyle indicators, gestational weight gain, or obstetric and perinatal outcomes did not differ between the two groups. An oral glucose tolerance test in the first half of pregnancy was pathological in 37.7% (n = 87/144) of intervention and 36.5% (n = 72/197) of control group women (p = 0.81). The total incidence of gestational diabetes diagnosed in the first or second half of pregnancy was 44.8% (107/239) in the intervention and 48.1% (111/231) in the control group (p = 0.48).
conclusionsThe high prevalence of impaired glucose metabolism was observed already in early pregnancy, which may have contributed to the lack of effect of the intervention.
Indexed as
Identifiers
30042471What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.