Evidence map›Paper›PMID 30042376›Full record

ArticleThe American journal of case reports2018

Fatal Disseminated Kaposi's Sarcoma in Two Patients with Human Immunodeficiency Virus (HIV) Infection.

Rafaela Barbirato Fardin, Luiz Arhur Calheiros Leite, Luanna Mayara Dos Santos Bezerra, Priscilla Maris Pereira Alves, Layanne Lima Dos Santos, Marília de Andrade Salvá, Antônio Luiz Soares Moura Rezende Filho, Gilberto Salustiano Lima, Juliana de Amorim Matos, Sônia Maria Soares Ferreira and 1 more

Open access · hybridAbstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Rafaela Barbirato FardinDepartment of Medicine, Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Luiz Arhur Calheiros LeiteDepartment of Infectious Disease, State University of Health Sciences of Alagoas (UNCISAL), Maceió, Alagoas, Brazil.
Luanna Mayara Dos Santos BezerraDepartment of Medicine, Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Priscilla Maris Pereira AlvesDepartment of Medicine, Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Layanne Lima Dos SantosDepartment of Medicine, Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Marília de Andrade SalváDepartment of Medicine, Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Antônio Luiz Soares Moura Rezende FilhoDepartment of Medicine, Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Gilberto Salustiano LimaDepartment of Infectious Disease, State University of Health Sciences of Alagoas (UNCISAL), Maceió, Alagoas, Brazil.
Juliana de Amorim MatosDepartment of Medicine, Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Sônia Maria Soares FerreiraDepartment of Medicine, Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Ducy Lily Joazeiro de Farias CostaDepartment of Medicine, Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Universidade Federal de Alagoas · BRUniversidade Estadual de Ciências da Saúde de Alagoas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Kaposi's sarcoma (KS) is a common condition in patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). In these patients, the occurrence of KS is reduced by treatment with highly active antiretroviral therapy (HAART). Fatal and disseminated KS is presented in two patients with HIV/AIDS. CASE REPORT A 25-year-old man and a 30-year-old man with HIV/AIDS presented with KS affecting the skin, oral cavity, gastrointestinal tract, liver, lungs, kidneys, adrenal glands, and bone. Both patients had a rapidly deteriorating clinical course associated with a low CD4 count and developed respiratory failure and death. CONCLUSIONS Fatal disseminated KS is associated with severe immunosuppression due to with a low CD4 count. The presentation of these two cases highlights the potentially aggressive clinical course of KS in patients with HIV/AIDS and reinforces the need for early diagnosis and rapid treatment with HAART.

Indexed as

Acquired Immunodeficiency SyndromeAdultCD4 Lymphocyte CountFatal OutcomeHumansMaleSarcoma, Kaposi

Identifiers

PMID30042376
PMCPMC6071497
OpenAlexW2901499173

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.