Evidence map›Paper›PMID 30042201›Full record

ArticlemBio2018

Low-Level Antimicrobials in the Medicinal Leech Select for Resistant Pathogens That Spread to Patients.

Lidia Beka, Matthew S Fullmer, Sophie M Colston, Michael C Nelson, Emilie Talagrand-Reboul, Paul Walker, Bradley Ford, Iain S Whitaker, Brigitte Lamy, Johann Peter Gogarten and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Applied and environmental microbiology · 2021
    Article
  7. TheInternational journal of molecular sciences · 2020
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Lidia BekaDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.
Matthew S FullmerDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.
Sophie M ColstonDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.
Michael C NelsonDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.ORCID 0000-0002-9042-5904
Emilie Talagrand-ReboulÉquipe Pathogènes Hydriques Santé Environnements, UMR 5569 HSM, Université de Montpellier, Montpellier, France.
Paul WalkerDepartment of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Bradley FordDepartment of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Iain S WhitakerInstitute of Life Sciences, Swansea University College of Medicine, Swansea, Wales, United Kingdom.
Brigitte LamyÉquipe Pathogènes Hydriques Santé Environnements, UMR 5569 HSM, Université de Montpellier, Montpellier, France.
Johann Peter GogartenDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.
Joerg GrafDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA joerg.graf@uconn.edu.ORCID 0000-0001-5320-2712
University of Connecticut · USUniversity of Iowa Hospitals and Clinics · USInserm · FRSwansea University · GBUniversité de Montpellier · FR

Funding

Functional Analysis of a Digestive-Tract Microbiome During Dietary ChangesR01GM095390 · NIGMS · UNIVERSITY OF CONNECTICUT STORRS · PI GRAF, JOERG, VISSCHER, PIETER T · 2011 to 2014
$1.5M
NIGMS NIH HHS R01 GM095390
6 · The paper itself

Abstract

Fluoroquinolones (FQs) and ciprofloxacin (Cp) are important antimicrobials that pollute the environment in trace amounts. Although Cp has been recommended as prophylaxis for patients undergoing leech therapy to prevent infections by the leech gut symbiont

Indexed as

Drug Resistance, Multiple, BacterialAeromonasAnimalsAnti-Bacterial AgentsCiprofloxacinDisease ReservoirsDNA GyraseFluoroquinolonesGastrointestinal MicrobiomeGram-Negative Bacterial InfectionsHirudo medicinalisHumansLeechingMicrobial Sensitivity TestsMutationAnti-Bacterial AgentsCiprofloxacinDNA GyraseFluoroquinolonesAeromonasantibiotic resistanceciprofloxacingenomicsleech therapymicrobiome

Identifiers

PMID30042201
PMCPMC6058295
OpenAlexW2883977863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.