Evidence map›Paper›PMID 30042185›Full record

ReviewJournal of medical genetics2018

Evolution of genetic assessment for BRCA-associated gynaecologic malignancies: a Canadian multisociety roadmap.

Jeanna M McCuaig, Tracy L Stockley, Patricia Shaw, Michael Fung-Kee-Fung, Alon D Altman, James Bentley, Marcus Q Bernardini, Beatrice Cormier, Hal Hirte, Katharina Kieser and 14 more

Abstract readReview
In one paragraph

Review in Journal of medical genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Practice guidelines forJournal of medical genetics · 2022
    Review
  8. Epithelial Ovarian Cancer: Providing Evidence of Predisposition Genes.International journal of environmental research and public health · 2022
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Response to Tomao, Panici, and Tomao.Journal of the National Cancer Institute · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jeanna M McCuaigFamilial Breast & Ovarian Cancer Clinic, Princess Margaret Hospital Cancer Centre, Toronto, Ontario, Canada.
Tracy L StockleyDivision of Clinical Laboratory Genetics and Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada.
Patricia ShawDepartment of Pathology, University Health Network, Toronto, Ontario, Canada.
Michael Fung-Kee-FungDepartment of Obstetrics and Gynecology, The Ottawa Hospital, Ottawa, Ontario, Canada.
Alon D AltmanDepartment of Gynecologic Oncology, University of Manitoba, CancerCare Manitoba, Winnipeg, Manitoba, Canada.
James BentleyDepartment of Obstetrics and Gynecology, Nova Scotia Health Authority, Halifix, Nova Scotia, Canada.
Marcus Q BernardiniDepartment of Gynecologic Oncology, Princess Margaret Hospital Cancer Centre, Toronto, Ontario, Canada.
Beatrice CormierDepartment of Obstetrics and Gynecology, Université de Montreal, Montreal, Quebec, Canada.
Hal HirteDepartment of Gynecologic Oncology, Juravinski Cancer Centre, Hamilton, Ontario, Canada.
Katharina KieserDepartment of Gynecologic Oncology, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada.
Andree MacMillanProvincial Medical Genetics Program, Eastern Health, St John's, Newfoundland and Labrador, Canada.
Wendy S MeschinoDepartment of Genetics, North York General Hospital, Toronto, Ontario, Canada.
Karen PanabakerMedical Genetics Program of Southwestern Ontario, London Health Sciences Centre, London, Ontario, Canada.
Renee PerrierDepartment of Medical Genetics, Alberta Children's Hospital, Calgary, Alberta, Canada.
Diane ProvencherDepartment of Obstetrics and Gynecology, Université de Montreal, Montreal, Quebec, Canada.
Kasmintan A SchraderHereditary Cancer Program, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.
Kimberly SerfasDepartment of Genetics and Metabolism, Winnipeg Regional Health Authority, Winnipeg, Manitoba, Canada.
Eva TomiakDepartment of Genetics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Nora WongDepartment of Medical Genetics, CIUSSS West-Central Montreal Jewish General Hospital, Montreal, Canada.
Sean S YoungDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Walter Henri GotliebDepartment of Gynecologic Oncology, Jewish General Hospital, Montreal, Quebec, Canada.
Paul HoskinsDepartment of Gynecologic Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.
Raymond H KimFamilial Breast & Ovarian Cancer Clinic, Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.ORCID 0000-0002-2147-8674
BRCA TtoT Community of Practice

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The landscape of genetic testing in ovarian cancer patients has changed dramatically in recent years. The therapeutic benefits of poly ADP-ribose polymerase (PARP) inhibitors in treatment of

Indexed as

MutationBRCA1 ProteinBRCA2 ProteinCanadaFemaleGenetic CounselingGenetic TestingHumansOvarian NeoplasmsPrecision MedicineBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, humanbrcagenetic counsellinggenetic testingovarian cancer

Identifiers

PMID30042185
PMCPMC6119348

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.