Evidence map›Paper›PMID 30042156›Full record

ArticleJournal of lipid research2018

CRISPR/Cas9-mediated

Ryota Izumi, Toru Kusakabe, Michio Noguchi, Hiroshi Iwakura, Tomohiro Tanaka, Takashi Miyazawa, Daisuke Aotani, Kiminori Hosoda, Kenji Kangawa, Kazuwa Nakao

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. A unified model for regulating lipoprotein lipase activity.Trends in endocrinology and metabolism: TEM · 2024
    Review
  5. Review
  6. Review
  7. Review
  8. Recent Advances in the Production of Genome-Edited Rats.International journal of molecular sciences · 2022
    Review
  9. Review
  10. Article
  11. Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8.American journal of physiology. Endocrinology and metabolism · 2021
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ryota IzumiMedical Innovation Center Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Diabetes, Endocrinology, and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Toru KusakabeMedical Innovation Center Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Endocrinology, Metabolism, and Hypertension, Clinical Research Institute, National Hospital Organization Kyoto Medical Center, Kyoto, Japan. Electronic address: kusakabe@kuhp.kyoto-u.ac.jp.
Michio NoguchiMedical Innovation Center Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hiroshi IwakuraMedical Innovation Center Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tomohiro TanakaMedical Innovation Center Kyoto University Graduate School of Medicine, Kyoto, Japan.
Takashi MiyazawaMedical Innovation Center Kyoto University Graduate School of Medicine, Kyoto, Japan.
Daisuke AotaniMedical Innovation Center Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kiminori HosodaMedical Innovation Center Kyoto University Graduate School of Medicine, Kyoto, Japan; Division of Endocrinology and Metabolism, Department of Lifestyle-Related Diseases, National Cerebral and Cardiovascular Center, Osaka, Japan.
Kenji KangawaMedical Innovation Center Kyoto University Graduate School of Medicine, Kyoto, Japan; National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.
Kazuwa NakaoMedical Innovation Center Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiopoietin-like protein (ANGPTL)8 is a liver- and adipocyte-derived protein that controls plasma triglyceride (TG) levels. Most animal studies have used mouse models. Here, we generated an

Indexed as

Gene Knockout TechniquesAdipogenesisAdiposityAngiopoietin-Like Protein 8Angiopoietin-like ProteinsAnimalsBase SequenceCRISPR-Cas SystemsDietFemaleGlucoseLipid MetabolismMaleMuscle, SkeletalMyocardiumObesityAngiopoietin-Like Protein 8Angiopoietin-like ProteinsAngptl8 protein, ratGlucoseTriglyceridesangiopoietin-like protein 8betatrophinclustered regulatory interspaced short palindromic repeat/clustered regulatory interspaced short palindromic repeat-associated protein 9dyslipidemiasfatty acid oxidationglucose metabolismlipase/lipoproteinlipoproteins/metabolismobesitytriglycerides

Identifiers

PMID30042156
PMCPMC6121927
OpenAlexW2883025088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.