Evidence map›Paper›PMID 30042151›Full record

ArticleCancer research2018

Mouse Homolog of the Human

Ji-Hoon Park, Jie Li, Matthew F Starost, Chengyu Liu, Jie Zhuang, Jichun Chen, Maria I Achatz, Ju-Gyeong Kang, Ping-Yuan Wang, Sharon A Savage and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. The Ashkenazi-Centric G334R Variant ofMolecular and cellular biology · 2024
    Article
  3. Emerging insights into ethnic-specific TP53 germline variants.Journal of the National Cancer Institute · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency.International journal of molecular sciences · 2022
    Article
  8. The Common GermlineCancer research · 2021
    Article
  9. Prevalence of the BrazilianFrontiers in genetics · 2021
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Ji-Hoon ParkCardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Jie LiCardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Matthew F StarostDivision of Veterinary Resources, NIH, Bethesda, Maryland.
Chengyu LiuTransgenic Core, NHLBI, NIH, Bethesda, Maryland.
Jie ZhuangCardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Jichun ChenHematology Branch, NHLBI, NIH, Bethesda, Maryland.
Maria I AchatzDivision of Cancer Epidemiology and Genetics, Clinical Genetics Branch, National Cancer Institute, Rockville, Maryland.
Ju-Gyeong KangCardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Ping-Yuan WangCardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
Sharon A SavageDivision of Cancer Epidemiology and Genetics, Clinical Genetics Branch, National Cancer Institute, Rockville, Maryland.
Paul M HwangCardiovascular Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland. hwangp@mail.nih.gov.
National Heart Lung and Blood Institute · USNational Institutes of Health · USNational Cancer Institute · UA

Funding

Clinical Genetic Studies of Familial and Hereditary Cancer SyndromesZIACP010144 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SAVAGE, SHARON A. · 2009 to 2025
$111.8M
NHLBI Animal Program DivisionZIGHL006020 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CLARK, TANNIA · 2009 to 2025
$47.3M
Transgenic CoreZICHL005907 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LIU, CHENGYU · 2010 to 2025
$25.8M
Mitochondrial regulation in cardiovascular and cancer biologyZIAHL005101 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI HWANG, PAUL M. · 2009 to 2025
$19.1M
Redox homeostasis in cancer and cardiovascular diseasesZIAHL006051 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI HWANG, PAUL M. · 2010 to 2025
$12.8M
Intramural NIH HHS ZIA HL006051
6 · The paper itself

Abstract

Inheritance of germline mutations in the tumor suppressor gene

Indexed as

AllelesAnimalsBrazilCarcinogenesisCell Transformation, NeoplasticDNA DamageFibroblastsGene Knock-In TechniquesGenetic Predisposition to DiseaseGerm-Line MutationHomozygoteHumansLiverLiver NeoplasmsMaleMiceTP53 protein, humanTrp53 protein, mouseTumor Suppressor Protein p53

Identifiers

PMID30042151
PMCPMC6139041
OpenAlexW2883477549

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.