Evidence map›Paper›PMID 30041694›Full record

SynthesisSystematic reviews2018

Preoperative exercise therapy for gastrointestinal cancer patients: a systematic review.

Sarah A Vermillion, Alston James, Robert D Dorrell, Peter Brubaker, Shannon L Mihalko, Adrienne R Hill, Clancy J Clark

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Systematic reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07713888 (The Effects of Multimodal Prehabilitation on Post-operative Recovery in Patients Undergoing Surgery for Upper Gastrointestinal Tract Cancer in Taiwan), which is not on this map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07713888 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Effects of Multimodal Prehabilitation on Post-operative Recovery in Patients Undergoing Surgery for Upper Gastrointestinal Tract Cancer in Taiwan

TypeinterventionalSponsorTaichung Tzu Chi HospitalRan2026 to 2027Enrolled40ConditionsSurgery of Upper Gastrointestinal Tract CancerArmsPrehabilitation
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 93 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effects of prehabilitation on postoperative outcomes in frail cancer patients undergoing elective surgery: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
  4. Trial
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. The effects of prehabilitation on body composition in patients undergoing multimodal therapy for esophageal cancer.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Exercise sustains the hallmarks of health.Journal of sport and health science · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sarah A VermillionBowman Gray Center for Medical Education, Wake Forest University School of Medicine, 475 Vine Street, Winston-Salem, NC, 27101, USA.
Alston JamesBowman Gray Center for Medical Education, Wake Forest University School of Medicine, 475 Vine Street, Winston-Salem, NC, 27101, USA.
Robert D DorrellBowman Gray Center for Medical Education, Wake Forest University School of Medicine, 475 Vine Street, Winston-Salem, NC, 27101, USA.
Peter BrubakerHealth and Exercise Science, Wake Forest University, Worrell Professional Center 2164B, PO BOX 7868, Winston-Salem, NC, 27109, USA.
Shannon L MihalkoHealth and Exercise Science, Wake Forest University, Worrell Professional Center 2164B, PO BOX 7868, Winston-Salem, NC, 27109, USA.
Adrienne R HillDepartment of Physical Medicine and Rehabilitation, Wake Forest Baptist Health, Medical Center Blvd, Winston-Salem, NC, 27157, USA.
Clancy J ClarkDivision of Surgical Oncology, Department of General Surgery, Wake Forest Baptist Health, Medical Center Blvd, Winston-Salem, NC, 27157, USA. cjclark@wakehealth.edu.ORCID 0000-0002-1258-2752
Wake Forest University · USAtrium Health Wake Forest Baptist · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastrointestinal cancer patients are susceptible to significant postoperative morbidity. The aim of this systematic review was to examine the effects of preoperative exercise therapy (PET) on patients undergoing surgery for GI malignancies.

methodsIn accordance with PRISMA statement, all prospective clinical trials of PET for patients diagnosed with GI cancer were identified by searching MEDLINE, Embase, Cochrane Library, ProQuest, PROSPERO, and DARE (March 8, 2017). The characteristics and outcomes of each study were extracted and reviewed. Risk of bias was evaluated using the Cochrane risk of bias tool by two independent reviewers.

resultsNine studies (534 total patients) were included in the systematic review. All interventions involved aerobic training but varied in terms of frequency, duration, and intensity. PET was effective in reducing heart rate, as well as increasing oxygen consumption and peak power output. The postoperative course was also improved, as PET was associated with more rapid recovery to baseline functional capacity after surgery.

conclusionsPET for surgical patients with gastrointestinal malignancies may improve physical fitness and aid in postoperative recovery.

Indexed as

Exercise TherapyGastrointestinal NeoplasmsHumansPreoperative CareCancerExercise therapyPreoperativeSurgery

Identifiers

PMID30041694
PMCPMC6058356
OpenAlexW2883052201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.