Evidence map›Paper›PMID 30041636›Full record

ArticleLipids in health and disease2018

MicroRNA-217 attenuates intima-media complex thickness of ascending aorta measured by ultrasound bio-microscopy and inhibits inflammation and lipid metabolism in atherosclerotic models of ApoE

Haina Liu, Xia Li, Yanpeng Song, Zhibin Wang

Open access · goldAbstract read
In one paragraph

Article in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Nutrients · 2022
    Article
  2. Article
  3. Review
  4. Article
  5. Molecular mechanisms and genetic regulation in atherosclerosis.International journal of cardiology. Heart & vasculature · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Haina LiuDepartment of Ultrasonography, The Affiliated Qingdao Municipal Hospital of Qingdao University, No.1 Jiaozhou Road, Qingdao, 266011, China.
Xia LiDepartment of Ultrasonography, The Affiliated Qingdao Municipal Hospital of Qingdao University, No.1 Jiaozhou Road, Qingdao, 266011, China.
Yanpeng SongDepartment of Ultrasonography, Jiaozhou Central Hospital of Qingdao, No.29 Xuzhou Road, Jiaozhou, 266300, China.
Zhibin WangDepartment of Ultrasonography, The Affiliated Hospital of Qingdao University, No.16 Jiangsu Road, Qingdao, 266003, China. wangzhibinkeyi@sina.com.
Qingdao University · CNAffiliated Hospital of Qingdao University · CNShuozhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle investigation was done to test the efficiency of microRNA-217 (miR-217) on atherosclerosis in vivo.

methodsApoE

resultsThe serum level of miR-217 was reduced in ApoE

conclusionmiR-217 could down-regulate IMT and modulate the inflammation and lipid metabolism process, which indicates that miR-217 could be a potential treatment option.

Indexed as

Carotid Intima-Media ThicknessAnimalsAortaAtherosclerosisDisease Models, AnimalGene Expression RegulationInflammationLipid MetabolismLipidsMice, Knockout, ApoEMicroRNAsMicroscopy, AcousticLipidsMicroRNAsMIRN-217 microRNA, mouseAtherosclerosisInflammationLipidMicroRNA-217Ultrasound bio-microscopy

Identifiers

PMID30041636
PMCPMC6058357
OpenAlexW2883215478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.