Evidence map›Paper›PMID 30041634›Full record

SynthesisLipids in health and disease2018

Circulating chemerin levels and gestational diabetes mellitus: a systematic review and meta-analysis.

Zhongwei Zhou, Hongmei Chen, Huixiang Ju, Mingzhong Sun

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  12. Is Chemerin Associated with Gestational Diabetes Mellitus? A Case-Control Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Article
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  15. Article
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  18. Novel Biomolecules in the Pathogenesis of Gestational Diabetes Mellitus.International journal of molecular sciences · 2021
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhongwei Zhou
Hongmei Chen
Huixiang Ju
Mingzhong SunDepartment of Clinical Laboratory, Affiliated Yancheng Hospital, School of Medicine, Southeast University, Jiangsu, 224001, Yancheng, People's Republic of China. 15189300678@163.com.
Yancheng Third People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChemerin is a novel adipokine which is associated with metabolic syndrome and type 2 diabetes mellitus. However, recent investigations regarding circulating chemerin levels in gestational diabetes mellitus (GDM) are conflicting. This meta-analysis is to evaluate and determine their associations.

methodsA systematic literature search was performed in PubMed, EMBASE and Web of Science up to 13 December 2017. Pooled standardized mean differences (SMD) and 95% confidence interval (CI) were calculated using a random-effect model.

resultsEleven studies comprising 742 GDM patients and 840 normal pregnant women were included. Circulating chemerin levels were increased in GDM patients compared with healthy pregnant women (SMD: 1.16; 95% CI: 0.29, 2.04; P = 0.009). Subgroup analyses revealed such difference was especially available in the groups of the second trimester (SMD: 1.47; 95% CI: 0.28, 2.67) and mean age < 30 years (SMD: 2.30; 95% CI: 0.69, 3.91) of GDM patients. There was significant heterogeneity among studies (I

conclusionsThe elevated levels of circulating chemerin were associated with GDM, which suggests it might play an important role in the pathogenetic mechanism of GDM.

Indexed as

AdultChemokinesDiabetes, GestationalFemaleHumansIntercellular Signaling Peptides and ProteinsPregnancyWhite PeopleChemokinesIntercellular Signaling Peptides and ProteinsRARRES2 protein, humanChemerinGestational diabetes mellitusInsulin resistanceMeta-analysisSystemic inflammation

Identifiers

PMID30041634
PMCPMC6058359
OpenAlexW2883329110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.