Evidence map›Paper›PMID 30041477›Full record

ReviewMarine drugs2018

Review of Chromatographic Bioanalytical Assays for the Quantitative Determination of Marine-Derived Drugs for Cancer Treatment.

Lotte van Andel, Hilde Rosing, Jan Hm Schellens, Jos H Beijnen

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Natural products against cancer: Review on phytochemicals from marine sources in preventing cancer.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lotte van AndelDepartment of Pharmacy & Pharmacology, Antoni van Leeuwenhoek, The Netherlands Cancer Institute and MC Slotervaart, 1066 CX Amsterdam, The Netherlands. l.v.andel@nki.nl.ORCID 0000-0002-2285-3384
Hilde RosingDepartment of Pharmacy & Pharmacology, Antoni van Leeuwenhoek, The Netherlands Cancer Institute and MC Slotervaart, 1066 CX Amsterdam, The Netherlands. h.rosing@nki.nl.
Jan Hm SchellensDivision of Pharmacology, Antoni van Leeuwenhoek, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands. j.schellens@nki.nl.
Jos H BeijnenDepartment of Pharmacy & Pharmacology, Antoni van Leeuwenhoek, The Netherlands Cancer Institute and MC Slotervaart, 1066 CX Amsterdam, The Netherlands. j.beijnen@nki.nl.
Slotervaartziekenhuis · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery of marine-derived compounds for the treatment of cancer has seen a vast increase over the last few decades. Bioanalytical assays are pivotal for the quantification of drug levels in various matrices to construct pharmacokinetic profiles and to link drug concentrations to clinical outcomes. This review outlines the different analytical methods that have been described for marine-derived drugs in cancer treatment hitherto. It focuses on the major parts of the bioanalytical technology, including sample type, sample pre-treatment, separation, detection, and quantification.

Indexed as

AnimalsAntineoplastic AgentsAquatic OrganismsBiological AssayChromatography, LiquidDrug DiscoveryHumansNeoplasmsAntineoplastic Agentsbioanalysiscancerchromatographymarine-derived drugs

Identifiers

PMID30041477
PMCPMC6071085
OpenAlexW2884174891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.