Trial reportNutrients2018
Effects of a High-Protein Diet Including Whole Eggs on Muscle Composition and Indices of Cardiometabolic Health and Systemic Inflammation in Older Adults with Overweight or Obesity: A Randomized Controlled Trial.
Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Health Effects of Increasing Protein Intake Above the Current Population Reference Intake in Older Adults: A Systematic Review of the Health Council of the Netherlands.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- Myoprotective Whole Foods, Muscle Health and Sarcopenia: A Systematic Review of Observational and Intervention Studies in Older Adults.Nutrients · 2020Pooled it
- Effect of egg consumption on inflammatory markers: a systematic review and meta-analysis of randomized controlled clinical trials.Journal of the science of food and agriculture · 2019Pooled it
- Trial
- Trial
- Protein Intake at Twice the RDA in Older Men Increases Circulatory Concentrations of the Microbiome Metabolite Trimethylamine-N-Oxide (TMAO).Nutrients · 2019Trial
- Estimating the effect of hypothetical dietary protein interventions on changes in body composition of postmenopausal women over 3 years using data from the Women's Health Initiative (WHI) Study: an emulated target trial.International journal of obesity (2005) · 2026Article
- Dietary and Behavioral Strategies for Weight Loss and Weight Loss Maintenance: A Narrative Review.Nutrients · 2025Review
- Protein intake and muscle mass of community-dwelling older adults: a cross-sectional study in Kigali, Rwanda.Scientific reports · 2025Article
- Role of protein intake in maintaining muscle mass composition among elderly females suffering from sarcopenia.Frontiers in nutrition · 2025Article
- Eggs: Healthy or Risky? A Review of Evidence from High Quality Studies on Hen's Eggs.Nutrients · 2023Review
- Effect of dietary protein intake on cognitive function in the elderly with chronic kidney disease: analysis of the National Health and Nutrition Examination Survey 2011-2014.Renal failure · 2023Article
- Effects of protein intake from an energy-restricted diet on the skeletal muscle composition of overweight and obese rats.Scientific reports · 2022Article
- The Health Benefits of Egg Protein.Nutrients · 2022Review
- The role of inflammation and the possibilities of inflammation reduction to prevent cardiovascular events.European heart journal open · 2022Review
- Food Consumption and Metabolic Risks in Young University Students.International journal of environmental research and public health · 2021Article
- Review
- Protein Intake and Human Health: Implications of Units of Protein Intake.Advances in nutrition (Bethesda, Md.) · 2021Article
- Effects of Combined High-Protein Diet and Exercise Intervention on Cardiometabolic Health in Middle-Aged Obese Adults: A Randomized Controlled Trial.Frontiers in cardiovascular medicine · 2021Article
- Dietary protein intake and obesity-associated cardiometabolic function.Current opinion in clinical nutrition and metabolic care · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Age-related increases in intermuscular adipose tissue (IMAT) impair muscle quality, decrease functional capacity, and promote several cardiometabolic and inflammatory disorders. Whether these age-related alterations in muscle composition improve by consuming a high-protein (HP) diet with whole eggs are unclear. This parallel-design, randomized-controlled trial assessed the effects of a 12-week eucaloric HP diet with three whole eggs per day (1.4 g protein kg
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.