ReviewBioengineering (Basel, Switzerland)2018
Trinity of Three-Dimensional (3D) Scaffold, Vibration, and 3D Printing on Cell Culture Application: A Systematic Review and Indicating Future Direction.
Review in Bioengineering (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Bone Regeneration with Mesenchymal Stem Cells in Scaffolds: Systematic Review of Human Clinical Trials.Stem cell reviews and reports · 2024Pooled it
- Microfluidics and organ-on-a-chip technologies: A systematic review of the methods used to mimic bone marrow.PloS one · 2020Pooled it
- Hydrogel-chitosan and polylactic acid-polycaprolactone bioengineered scaffolds for reconstruction of mandibular defects: a preclinicalFrontiers in bioengineering and biotechnology · 2024Article
- Characterization of Mechanical and Cellular Effects of Rhythmic Vertical Vibrations on Adherent Cell Cultures.Bioengineering (Basel, Switzerland) · 2023Article
- Fabrication of a Low-Cost Microfluidic Device for High-Throughput Drug Testing on Static and Dynamic Cancer Spheroid Culture Models.Diagnostics (Basel, Switzerland) · 2023Article
- Application of Biocompatible Scaffolds in Stem-Cell-Based Dental Tissue Engineering.Advances in experimental medicine and biology · 2023Review
- Preparation of a 3D printable high-performance GelMA hydrogel loading with magnetic cobalt ferrite nanoparticles.Frontiers in bioengineering and biotechnology · 2023Article
- Design of 3D-Printed Electronic Fiber Optic Sensor to Detect Rhodamine B Reagent: An Initiation to Potential Virus Detection.Biomimetics (Basel, Switzerland) · 2022Article
- Review
- A Review of Conductive Carbon Materials for 3D Printing: Materials, Technologies, Properties, and Applications.Materials (Basel, Switzerland) · 2021Review
- Polysaccharide hydrogel based 3D printed tumor models for chemotherapeutic drug screening.Scientific reports · 2021Article
- A State-of-the-Art of Functional Scaffolds for 3D Nervous Tissue Regeneration.Frontiers in bioengineering and biotechnology · 2021Review
- Article
- 3D Culture Systems for Exploring Cancer Immunology.Cancers · 2020Review
- Construction of higher-order cellular microstructures by a self-wrapping co-culture strategy using a redox-responsive hydrogel.Scientific reports · 2020Article
- The Research Advance of Cell BridgesFrontiers in bioengineering and biotechnology · 2020Review
- Characterization and printability of Sodium alginate -Gelatin hydrogel for bioprinting NSCLC co-culture.Scientific reports · 2019Article
- Modifying the Tumour Microenvironment: Challenges and Future Perspectives for Anticancer Plasma Treatments.Cancers · 2019Review
- A Systematic Study on Design Initiation of Conceptual 3DPVS.Biomimetics (Basel, Switzerland) · 2019Article
- Introducing the Language of "Relativity" for New Scaffold Categorization.Bioengineering (Basel, Switzerland) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell culture and cell scaffold engineering have previously developed in two directions. First can be 'static into dynamic', with proven effects that dynamic cultures have benefits over static ones. Researches in this direction have used several mechanical means, like external vibrators or shakers, to approximate the dynamic environments in real tissue, though such approaches could only partly address the issue. Second, can be '2D into 3D', that is, artificially created three-dimensional (3D) passive (also called 'static') scaffolds have been utilized for 3D cell culture, helping external culturing conditions mimic real tissue 3D environments in a better way as compared with traditional two-dimensional (2D) culturing. In terms of the fabrication of 3D scaffolds, 3D printing (3DP) has witnessed its high popularity in recent years with ascending applicability, and this tendency might continue to grow along with the rapid development in scaffold engineering. In this review, we first introduce cell culturing, then focus 3D cell culture scaffold, vibration stimulation for dynamic culture, and 3DP technologies fabricating 3D scaffold. Potential interconnection of these realms will be analyzed, as well as the limitations of current 3D scaffold and vibration mechanisms. In the recommendation part, further discussion on future scaffold engineering regarding 3D vibratory scaffold will be addressed, indicating 3DP as a positive bridging technology for future scaffold with integrated and localized vibratory functions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.