ArticleCurrent protocols in bioinformatics2018
Searching ECOD for Homologous Domains by Sequence and Structure.
Article in Current protocols in bioinformatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
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- Target classification in the 14th round of the critical assessment of protein structure prediction (CASP14).Proteins · 2021Article
- Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum.Nature communications · 2019Article
- Predicting Sequence Features, Function, and Structure of Proteins Using MESSA.Current protocols in bioinformatics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
ECOD is a database of evolutionary domains from structures deposited in the PDB. Domains in ECOD are classified by a mixed manual/automatic method wherein the bulk of newly deposited structures are classified automatically by protein-protein BLAST. Those structures that cannot be classified automatically are referred to manual curators who use a combination of alignment results, functional analysis, and close reading of the literature to generate novel assignments. ECOD differs from other structural domain resources in that it is continually updated, classifying thousands of proteins per week. ECOD recognizes homology as its key organizing concept, rather than structural or sequence similarity alone. Such a classification scheme provides functional information about proteins of interest by placing them in the correct evolutionary context among all proteins of known structure. This unit demonstrates how to access ECOD via the Web and how to search the database by sequence or structure. It also details the distributable data files available for large-scale bioinformatics users. © 2018 by John Wiley & Sons, Inc.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.