Evidence map›Paper›PMID 30039565›Full record

ArticleChemphyschem : a European journal of chemical physics and physical chemistry2018

Heterogeneous Parahydrogen Pairwise Addition to Cyclopropane.

Oleg G Salnikov, Kirill V Kovtunov, Panayiotis Nikolaou, Larisa M Kovtunova, Valerii I Bukhtiyarov, Igor V Koptyug, Eduard Y Chekmenev

Abstract read
In one paragraph

Article in Chemphyschem : a European journal of chemical physics and physical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. HeterogeneousChemphyschem : a European journal of chemical physics and physical chemistry · 2021
    Article
  4. Bridging the Gap: From Homogeneous to Heterogeneous Parahydrogen-induced Hyperpolarization and Beyond.Chemphyschem : a European journal of chemical physics and physical chemistry · 2021
    Review
  5. Article
  6. Parahydrogen-Induced Hyperpolarization of Gases.Angewandte Chemie (International ed. in English) · 2020
    Review
  7. Relaxation Dynamics of Nuclear Long-Lived Spin States in Propane and Propane-dThe journal of physical chemistry. C, Nanomaterials and interfaces · 2019
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Oleg G SalnikovInternational Tomography Center, SB RAS, 3 A Institutskaya st., Novosibirsk, 630090, Russia.ORCID 0000-0003-2266-7335
Kirill V KovtunovInternational Tomography Center, SB RAS, 3 A Institutskaya st., Novosibirsk, 630090, Russia.ORCID 0000-0001-7577-9619
Panayiotis NikolaouVanderbilt University Institute of Imaging Science (VUIIS), Department of Radiology, Department of Biomedical Engineering, and Vanderbilt-Ingram Cancer Center (VICC), Vanderbilt University Medical Center, Nashville, TN, 37232-2310, United States.
Larisa M KovtunovaNovosibirsk State University, 2 Pirogova st., Novosibirsk, 630090, Russia.ORCID 0000-0003-0922-6594
Valerii I BukhtiyarovNovosibirsk State University, 2 Pirogova st., Novosibirsk, 630090, Russia.ORCID 0000-0003-4382-1207
Igor V KoptyugInternational Tomography Center, SB RAS, 3 A Institutskaya st., Novosibirsk, 630090, Russia.ORCID 0000-0003-3480-7649
Eduard Y ChekmenevVanderbilt University Institute of Imaging Science (VUIIS), Department of Radiology, Department of Biomedical Engineering, and Vanderbilt-Ingram Cancer Center (VICC), Vanderbilt University Medical Center, Nashville, TN, 37232-2310, United States.ORCID 0000-0002-8745-8801
Novosibirsk State University · RURussian Academy of Sciences · RUVanderbilt University Medical Center · US

Funding

Pure parahydrogen-enhanced metabolic MRI contrast agents for molecular imagingR21EB020323 · NIBIB · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI CHEKMENEV, EDUARD, GOODSON, BOYD M · 2015 to 2016
$416k
Magnetic Resonance Spectroscopy and Molecular Imaging of Metabolic Pathways in CancerR21CA220137 · NCI · WAYNE STATE UNIVERSITY · PI CHEKMENEV, EDUARD · 2017 to 2019
$390k
Federal Agency for Scientific Organizations 0333-2017-0002NCI NIH HHS R21 CA220137NIBIB NIH HHS R21 EB020323Russian Science Foundation 17-73-20030SB RAS integrated research program 0333-2018-0006/II.1.13
6 · The paper itself

Abstract

Hyperpolarized gases revolutionize functional pulmonary imaging. Hyperpolarized propane is a promising emerging contrast agent for pulmonary MRI. Unlike hyperpolarized noble gases, proton-hyperpolarized propane gas can be imaged using conventional MRI scanners with proton imaging capability. Moreover, it is non-toxic odorless anesthetic. Furthermore, propane hyperpolarization can be accomplished by pairwise addition of parahydrogen to propylene. Here, we demonstrate the feasibility of propane hyperpolarization via hydrogenation of cyclopropane with parahydrogen.

Indexed as

CatalysisCyclopropanesFeasibility StudiesHydrogenHydrogenationMagnetic Resonance ImagingMagnetic Resonance SpectroscopyProtonscyclopropaneCyclopropanesHydrogenProtonscontrast agentcyclopropanehydrogenationhyperpolarizationparahydrogen-induced polarization

Identifiers

PMID30039565
PMCPMC6197887
OpenAlexW2884826061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.