Evidence map›Paper›PMID 30039497›Full record

ArticleDrug delivery and translational research2018

Atorvastatin calcium inclusion complexation with polysaccharide arabinogalactan and saponin disodium glycyrrhizate for increasing of solubility and bioavailability.

Ruiping Kong, Xingyi Zhu, Elizaveta S Meteleva, Nikolay E Polyakov, Mikhail V Khvostov, Dmitry S Baev, Tatjana G Tolstikova, Alexander V Dushkin, Weike Su

Abstract read
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In one paragraph

Article in Drug delivery and translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Ruiping KongCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, People's Republic of China.
Xingyi ZhuCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, People's Republic of China.
Elizaveta S MetelevaInstitute of Solid State Chemistry and Mechanochemistry, SB RAS, Novosibirsk, Russia, 630128.
Nikolay E PolyakovInstitute of Chemical Kinetics and Combustion, SB RAS, Novosibirsk, Russia.
Mikhail V KhvostovN.N. Vorozhtsov Institute of Organic Chemistry, SB RAS, Novosibirsk, Russia.
Dmitry S BaevN.N. Vorozhtsov Institute of Organic Chemistry, SB RAS, Novosibirsk, Russia.
Tatjana G TolstikovaN.N. Vorozhtsov Institute of Organic Chemistry, SB RAS, Novosibirsk, Russia.
Alexander V DushkinCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, People's Republic of China. dushkin@solid.nsc.ru.
Weike SuCollaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, People's Republic of China. pharmlab@zjut.edu.cn.
Zhejiang University of Technology · CNInstitute of Solid State Chemistry and Mechanochemistry · RUNovosibirsk State University · RUInstitute of Chemical Kinetics and Combustion · RUNovosibirsk Institute of Organic Chemistry · RU

Funding

the state assignment to ISSCM SB RAS 0301-2016-0017
6 · The paper itself

Abstract

The aim of the present investigation was to enhance the solubility and dissolution of atorvastatin calcium (ATV), a poorly water-soluble drug with larch polysaccharide arabinogalactan (AG) and disodium glycyrrhizate (Na

Indexed as

Administration, OralAnimalsAtorvastatinBiological AvailabilityDisease Models, AnimalDrug Delivery SystemsDrug LiberationDrug StabilityGalactansGlycyrrhizic AcidHypercholesterolemiaMaleMolecular WeightRatsSaponinsSolubilityarabinogalactanAtorvastatinGalactansGlycyrrhizic AcidSaponinsArabinogalactanAtorvastatin calciumDisodium glycyrrhizinMechanochemistrySolubilitySupramolecular complexes

Identifiers

PMID30039497
OpenAlexW2884975589

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.