ArticleDrugs & aging2018
Kidney Function, Polypharmacy, and Potentially Inappropriate Medication Use in a Community-Based Cohort of Older Adults.
Article in Drugs & aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- A systematically collated library of prescribing safety indicators for people with chronic kidney disease.BMC nephrology · 2020Pooled it
- Association Between Physical Therapy and Mortality in Older Patients with Heart Failure and Chronic Kidney Disease.Journal of clinical medicine · 2026Article
- Drug prescription before and after dialysis initiation in older patients: a nationwide study.BMC geriatrics · 2026Article
- Prevalence of Beers Criteria Potentially Inappropriate Medication Use and Associated Factors among Three US Studies.Drugs & aging · 2026Article
- Polypharmacy and Potentially Inappropriate Medications in Adults ≥75 Years of Age by Dementia and Frailty Status: The ARIC Study.Mayo Clinic proceedings · 2025Article
- The Acute Kidney Intervention and Pharmacotherapy (AKIP) List: Standardized List of Medications That Are Renally Eliminated and Nephrotoxic in the Acutely Ill.The Annals of pharmacotherapy · 2025Article
- Prescribing patterns and medication costs in patients on maintenance haemodialysis and peritoneal dialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Article
- Classification of chronic kidney disease in older Australian adults by the CKD-EPI 2009 and 2021 equations: secondary analysis of ASPREE study data.The Medical journal of Australia · 2025Article
- Using Chronic Kidney Disease as a Model Framework to Estimate Healthcare-Related Environmental Impact.Advances in therapy · 2025Article
- Medications for community pharmacists to dose adjust or avoid to enhance prescribing safety in individuals with advanced chronic kidney disease: a scoping review and modified Delphi.BMC nephrology · 2024Article
- Evolving Concepts of Pain Management in Elderly Patients.Current pain and headache reports · 2024Review
- Prevalence and Risk Factors of Inappropriate Drug Dosing among Older Adults with Dementia or Cognitive Impairment and Renal Impairment: A Systematic Review.Journal of clinical medicine · 2024Review
- Association between polypharmacy and chronic kidney disease among community-dwelling older people: a longitudinal study in southern China.BMC nephrology · 2024Article
- Effect modification of polypharmacy on incident frailty by chronic kidney disease in older adults.BMC geriatrics · 2024Article
- Potentially inappropriate medication prescribing based on 2019 Beers criteria and the impact of pharmacist intervention in elderly patients with kidney diseases: A report from Iran.Health science reports · 2024Article
- Review
- Prevalence and factors associated with polypharmacy among patients with rheumatoid arthritis: a single-centre, cross-sectional study.Clinical rheumatology · 2023Article
- The association between socioeconomic status and use of potentially inappropriate medications in older adults.Journal of the American Geriatrics Society · 2023Article
- Association of polypharmacy with incidence of CKD: a retrospective cohort study.Clinical and experimental nephrology · 2023Article
- Comorbidity, life-style factors and healthcare utilization in incident chronic kidney disease: sex-specific analyses of claims data.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023Observational
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundChronic kidney disease (CKD) afflicts many older adults and increases the risk for medication-related adverse events.
objectiveThe aim of this study was to assess the prevalence and associated morbidity and mortality of polypharmacy (use of several medications concurrently), and potentially inappropriate medication (PIM) use in older adults, looking for differences by CKD status.
methodsWe quantified medication and PIM use (from Beers criteria, the Screening Tool of Older People's Prescriptions, and Micromedex
resultsMean age at baseline was 76 (± 5) years, 59% were female, and 29% had CKD (eGFR < 60 ml/min/1.73 m
conclusionPolypharmacy and PIM use were common, with greater numbers of medications associated with higher risk of hospitalization and death; relative risks were similar for those with and without CKD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.