Evidence map›Paper›PMID 30039259›Full record

ArticleDysphagia2019

Volumetric Changes to the Pharynx in Healthy Aging: Consequence for Pharyngeal Swallow Mechanics and Function.

Sonja M Molfenter, Charles Lenell, Cathy L Lazarus

Erratum issuedAbstract read
In one paragraph

Article in Dysphagia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 52 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  11. Preliminary Exploration of Variations in Measures of Pharyngeal Area During Nonswallowing Tasks.Journal of speech, language, and hearing research : JSLHR · 2024
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  12. Normal values for swallow events during endoscopic evaluation of swallowing: a preliminary study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Sonja M MolfenterDepartment of Communicative Sciences & Disorders, NYU Steinhardt, New York, NY, USA. smm16@nyu.edu.ORCID http://orcid.org/0000-0002-1494-661X
Charles LenellDepartment of Communicative Sciences & Disorders, NYU Steinhardt, New York, NY, USA.
Cathy L LazarusDepartment of Otolaryngology Head & Neck Surgery, Mount Sinai Beth Israel, THANC Foundation, New York, NY, USA.

Funding

Exploring the relationship between age-related pharyngeal atrophy and difficulty swallowing.R21DC015067 · NIDCD · NEW YORK UNIVERSITY · PI MOLFENTER, SONJA M · 2016 to 2017
$413k
NIDCD NIH HHS R21 DC015067
6 · The paper itself

Abstract

Pharyngeal lumen volume is prone to increase as a consequence of pharyngeal muscle atrophy in aging. Yet, the impact of this on swallowing mechanics and function is poorly understood. We examined the relationship between pharyngeal volume and pharyngeal swallowing mechanics and function in a sample of healthy community-dwelling seniors. Data were collected from 44 healthy seniors (21 male, mean age = 76.9, SD = 7.1). Each participant swallowed 9 boluses of barium (3 × 5 ml thin, 3 × 20 ml thin, 3 × 5 ml nectar). Pharyngeal shortening, pharyngeal constriction, pyriform sinus and vallecular residue were quantified from lateral view videofluorosopic swallowing studies. Pharyngeal lumen volume was captured during an oral breathing task with acoustic pharyngometry. In addition, within-participant measures of strength and anthropometrics were collected. Four linear mixed effects regression models were run to study the relationship between pharyngeal volume and pharyngeal constriction, pharyngeal shortening, pyriform sinus residue, and vallecular residue while controlling for bolus condition, age, sex, and posterior tongue strength. Increasing pharyngeal lumen volume was significantly related to worse constriction and vallecular residue. In general, larger and thicker boluses resulted in worse pharyngeal constriction and residue. Pharyngeal shortening was only significantly related to posterior tongue strength. Our work establishes the utility of acoustic pharyngometry to monitor pharyngeal lumen volume. Increasing pharyngeal lumen volume appears to impact both pharyngeal swallowing mechanics and function in a sample of healthy, functional seniors.

Indexed as

AgedBarium RadioisotopesDeglutitionFemaleHealthy AgingHealthy VolunteersHumansMaleMuscular AtrophyOrgan SizePharyngeal MusclesPharynxRegression AnalysisViscosityBarium RadioisotopesAcoustic pharyngometryAgingAtrophyDeglutitionDeglutition disordersDysphagiaPharyngeal constrictionPharyngeal shorteningPharynxResidueSarcopeniaSwallowing

Identifiers

PMID30039259
PMCPMC6344328

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.