Evidence map›Paper›PMID 30038942›Full record

ArticleMolecular therapy. Methods & clinical development2018

HDAd5/35

Chang Li, Nikoletta Psatha, Sucheol Gil, Hongjie Wang, Thalia Papayannopoulou, André Lieber

Abstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Protective antigen-mediated delivery of an anti-CRISPR protein for precision genome editing.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Mechanism of Cas9 inhibition by AcrIIA11.Nucleic acids research · 2025
    Article
  6. Review
  7. Introducing a hemoglobin G-Makassar variant in HSCs by in vivo base editing treats sickle cell disease in mice.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  8. Article
  9. Article
  10. Comprehensive deletion scan of anti-CRISPR AcrIIA4 reveals essential and dispensable domains for Cas9 inhibition.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.Signal transduction and targeted therapy · 2024
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chang LiDivision of Medical Genetics, Department of Medicine, University of Washington, Box 357720, Seattle, WA 98195, USA.
Nikoletta PsathaDivision of Medical Genetics, Department of Medicine, University of Washington, Box 357720, Seattle, WA 98195, USA.
Sucheol GilDivision of Medical Genetics, Department of Medicine, University of Washington, Box 357720, Seattle, WA 98195, USA.
Hongjie WangDivision of Medical Genetics, Department of Medicine, University of Washington, Box 357720, Seattle, WA 98195, USA.
Thalia PapayannopoulouDivision of Hematology, Department of Medicine, University of Washington, Seattle, WA 98195, USA.
André LieberDivision of Medical Genetics, Department of Medicine, University of Washington, Box 357720, Seattle, WA 98195, USA.

Funding

Stem Cell and Transplantation BiologyU54DK106829 · NIDDK · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DEREK L STIREWALT · 2015 to 2026
$9.1M
In Vivo Hematopoietic Stem Cell Gene Therapy of Beta-Thalassemia and Sickle Cell DiseaseR01HL130040 · NHLBI · UNIVERSITY OF WASHINGTON · PI LIEBER, ANDRE MICHAEL · 2016 to 2024
$4.3M
Approach for in vivo gene delivery into hematopoietic stem cells for hemophilia A therapyR01HL141781 · NHLBI · UNIVERSITY OF WASHINGTON · PI LIEBER, ANDRE MICHAEL · 2018 to 2021
$2.3M
In vivo anti-PD1 gene therapyR21CA204036 · NCI · UNIVERSITY OF WASHINGTON · PI LIEBER, ANDRE MICHAEL · 2017 to 2018
$371k
Hematopoietic stem cell based gene therapy of breast cancerR21CA193077 · NCI · UNIVERSITY OF WASHINGTON · PI LIEBER, ANDRE MICHAEL · 2015 to 2016
$370k
NCI NIH HHS R21 CA193077NCI NIH HHS R21 CA204036NHLBI NIH HHS R01 HL130040NHLBI NIH HHS R01 HL141781NIDDK NIH HHS U54 DK106829
6 · The paper itself

Abstract

We generated helper-dependent HDAd5/35

Identifiers

PMID30038942
PMCPMC6054697

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.