Evidence map›Paper›PMID 30038934›Full record

ArticleMolecular therapy. Methods & clinical development2018

A New Method for Reactivating and Expanding T Cells Specific for

Paul Castillo, Kaylor E Wright, Dimitrios P Kontoyiannis, Thomas Walsh, Shabnum Patel, Elizabeth Chorvinsky, Swaroop Bose, Yasmin Hazrat, Bilal Omer, Nathaniel Albert and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The Impact of Dimitrios P. Kontoyiannis on Mucormycosis Research.Journal of fungi (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Mucormycosis in 2023: an update on pathogenesis and management.Frontiers in cellular and infection microbiology · 2023
    Review
  10. Review
  11. The generation and application of antigen-specific T cell therapies for cancer and viral-associated disease.Molecular therapy : the journal of the American Society of Gene Therapy · 2022
    Review
  12. Review
  13. Review
  14. Mucormycosis and COVID-19 pandemic: Clinical and diagnostic approach.Journal of infection and public health · 2022
    Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Paul CastilloCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA.
Kaylor E WrightSheikh Zayed Institute and Center for Cancer and Immunology Research, Children's National Health System, Washington, DC 20010, USA.
Dimitrios P KontoyiannisDepartment of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Thomas WalshDepartment of Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
Shabnum PatelSheikh Zayed Institute and Center for Cancer and Immunology Research, Children's National Health System, Washington, DC 20010, USA.
Elizabeth ChorvinskySheikh Zayed Institute and Center for Cancer and Immunology Research, Children's National Health System, Washington, DC 20010, USA.
Swaroop BoseSheikh Zayed Institute and Center for Cancer and Immunology Research, Children's National Health System, Washington, DC 20010, USA.
Yasmin HazratCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA.
Bilal OmerCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA.
Nathaniel AlbertDepartment of Infectious Diseases, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Ann M LeenCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA.
Cliona M RooneyCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX 77030, USA.
Catherine M BollardSheikh Zayed Institute and Center for Cancer and Immunology Research, Children's National Health System, Washington, DC 20010, USA.
Conrad Russell Y CruzSheikh Zayed Institute and Center for Cancer and Immunology Research, Children's National Health System, Washington, DC 20010, USA.
Children's National · USBaylor College of Medicine · USThe University of Texas MD Anderson Cancer Center · USCornell University · US

Funding

PEDIATRIC ONCOLOGY CLINICAL RESEARCH TRAINING PROGRAMK12CA090433 · NCI · BAYLOR COLLEGE OF MEDICINE · PI CARL E ALLEN, Donald W. Parsons · 2002 to 2026
$18.5M
NCI NIH HHS K12 CA090433
6 · The paper itself

Abstract

Mucormycosis is responsible for an increasing proportion of deaths after allogeneic bone marrow transplantation. Because this disease is associated with severe immunodeficiency and has shown resistance to even the newest antifungal agents, we determined the feasibility of reactivating and expanding

Indexed as

antigen presentation/processingcytokinescytotoxic T cellsfungalimmune reconstitutiontransplantation

Identifiers

PMID30038934
PMCPMC6054701
OpenAlexW2791555747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.