ArticleNPJ biofilms and microbiomes2018
Effect of divalent ions and a polyphosphate on composition, structure, and stiffness of simulated drinking water biofilms.
Article in NPJ biofilms and microbiomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Microbial extracellular polymeric substances in the environment, technology and medicine.Nature reviews. Microbiology · 2025Review
- Biofilm Formation, Modulation, and Transcriptomic Regulation Under Stress Conditions inInternational journal of molecular sciences · 2025Article
- Ln-MOF in production of durable antimicrobial and UV-Protective fluorescent cotton fabric for potential application in military textiles.Scientific reports · 2025Article
- Bacteria Colonies Modify Their Shear and Compressive Mechanical Properties in Response to Different Growth Substrates.ACS applied bio materials · 2024Article
- Quantification of Enzymatic Biofilm Removal Using the Sauerbrey Equation: Application to the Case ofACS omega · 2024Article
- Influence of phosphate on bacterial release from activated carbon point-of-use filters and on biofilm characteristics.The Science of the total environment · 2024Article
- Assessing the Impacts of Lead Corrosion Control on the Microbial Ecology and Abundance of Drinking-Water-Associated Pathogens in a Full-Scale Drinking Water Distribution System.Environmental science & technology · 2023Article
- Glycerol Droplet Spreading on Growing Bacillus Subtilis Biofilms.Micromachines · 2023Article
- Effects of phosphate and silicate on stiffness and viscoelasticity of mature biofilms developed with simulated drinking water.Biofouling · 2023Article
- Multivalent network modifier upregulates bioactivity of multispecies biofilm-resistant polyalkenoate cement.Bioactive materials · 2022Article
- Biofilm Formation, Production of Matrix Compounds and Biosorption of Copper, Nickel and Lead by Different Bacterial Strains.Frontiers in microbiology · 2021Article
- Effect of Nonphosphorus Corrosion Inhibitors on Biofilm Pore Structure and Mechanical Properties.Environmental science & technology · 2020Article
- Microbial Degradation of Plastic in Aqueous Solutions Demonstrated by COInternational journal of molecular sciences · 2020Article
- Metal ions weaken the hydrophobicity and antibiotic resistance ofNPJ biofilms and microbiomes · 2020Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
The biofilm chemical and physical properties in engineered systems play an important role in governing pathogen transmission, fouling facilities, and corroding metal surfaces. Here, we investigated how simulated drinking water biofilm chemical composition, structure, and stiffness responded to the common scale control practice of adjusting divalent ions and adding polyphosphate. Magnetomotive optical coherence elastography (MM-OCE), a tool developed for diagnosing diseased tissues, was used to determine biofilm stiffness in this study. MM-OCE, together with atomic force microscopy (AFM), revealed that the biofilms developed from a drinking water source with high divalent ions were stiffer compared to biofilms developed either from the drinking water source with low divalent ions or the water containing a scale inhibitor (a polyphosphate). The higher stiffness of biofilms developed from the water containing high divalent ions was attributed to the high content of calcium carbonate, suggested by biofilm composition examination. In addition, by examining the biofilm structure using optical coherence tomography (OCT), the highest biofilm thickness was found for biofilms developed from the water containing the polyphosphate. Compared to the stiff biofilms developed from the water containing high divalent ions, the soft and thick biofilms developed from the water containing polyphosphate will be expected to have higher detachment under drinking water flow. This study suggested that water chemistry could be used to predict the biofilm properties and subsequently design the microbial safety control strategies.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.