ArticleTranslational neurodegeneration2018
Cognitive characteristics in Chinese non-demented PD patients based on gender difference.
Article in Translational neurodegeneration, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sex differences in alpha-synucleinopathies: a systematic review.Frontiers in neurology · 2023Pooled it
- Glymphatic alteration in NAFLD patient: a preliminary magnetic resonance imaging study based on DTI-ALPS.BMC psychiatry · 2025Article
- Exploring the relationships between clinical manifestations and sex hormones, thyroid hormones, and menstrual factors in female Parkinson's disease patients.Frontiers in medicine · 2025Article
- Sex differences of fall-risk-increasing drugs in the middle-aged and elderly: a descriptive, cross-sectional study of FDA adverse event reporting system.Scientific reports · 2024Article
- Decreased retinal vascular density is associated with cognitive impairment in CADASIL: an optical coherence tomography angiography study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Sex Differences in the Speech of Persons With and Without Parkinson's Disease.American journal of speech-language pathology · 2024Article
- Patients with Parkinson's disease demonstrate deficits in visual-spatial memory in the Chinese Visual Retention Test.Brain and behavior · 2024Article
- Diffusion prepared pseudo-continuous arterial spin labeling reveals blood-brain barrier dysfunction in patients with CADASIL.European radiology · 2023Article
- Sex Differences in Parkinson's Disease: From Bench to Bedside.Brain sciences · 2022Article
- Executive Performance Is Associated With Rest-Activity Rhythm in Nurses Working Rotating Shifts.Frontiers in neuroscience · 2022Article
- The Impact of Sex on the Neurocognitive Functions of Patients with Parkinson's Disease.Brain sciences · 2021Article
- Corneal nerve fiber loss relates to cognitive impairment in patients with Parkinson's disease.NPJ Parkinson's disease · 2021Article
- Potential use of corneal confocal microscopy in the diagnosis of Parkinson's disease associated neuropathy.Translational neurodegeneration · 2020Review
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCognitive impairment is one of the non-motor symptoms in Parkinson's disease (PD). In the present study, we aim to examine the cognitive function of non-demented Parkinson's disease patients and compare the results between male and female patients as well as control groups in search of any gender effect.
methodsSixty PD Patients (30 males and 30 females) from the Movement Disorders Clinic at Huashan Hospital Affiliated to Fudan University were recruited to participate in the study. One hundred age and gender matched control subjects without neurological or psychiatric disorders were voluntarily recruited. The participants were administered measures of cognition in five domains including memory, language, spatial processing abilities, attention and executive function.
resultsPD patients attained significantly lower scores in the visual spatial function, language and attention/executive function compared with the control group. Anti-parkinsonian treated patients performed worse in Rey-copy score, Clock Drawing Test (CDT) and Verbal Fluency-City than untreated ones. In regard to gender differences, though no general cognitive differences were found in Mini-mental State Examination (MMSE), men surpassed women on Boston naming test (BNT) while women were superior on Auditory Verbal Learning Test-long (AVLT) delayed cued recall test.
conclusionsCognitive impairments were common in PD patients even in the absence of dementia. PD patients with anti-parkinsonian medication had worse cognitive impairment than untreated patients. Genders may have different manifestations of cognitive impairment in PD patients.
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