Evidence map›Paper›PMID 30038756›Full record

ArticleEcology and evolution2018

Age- and quality-dependent DNA methylation correlate with melanin-based coloration in a wild bird.

Carl D Soulsbury, Anssi Lipponen, Kristie Wood, Charles A Mein, Joseph I Hoffman, Christophe Lebigre

Open access · goldAbstract read
In one paragraph

Article in Ecology and evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Carl D SoulsburySchool of Life Sciences University of Lincoln Brayford Pool Lincoln UK.ORCID 0000-0001-8808-5210
Anssi LipponenDepartment of Biological and Environmental Science University of Jyväskylä Finland.ORCID 0000-0002-4403-9084
Kristie WoodThe Genome Centre, Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK.
Charles A MeinThe Genome Centre, Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK.
Joseph I HoffmanDepartment of Animal Behaviour University of Bielefeld Bielefeld Germany.ORCID 0000-0001-5895-8949
Christophe LebigreFrench Research Institute for the Exploitation of the Sea Plouzané France.ORCID 0000-0001-6119-2534
Queen Mary University of London · GBBielefeld University · DEUniversity of Eastern Finland · FIUniversity of Lincoln · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Secondary sexual trait expression can be influenced by fixed individual factors (such as genetic quality) as well as by dynamic factors (such as age and environmentally induced gene expression) that may be associated with variation in condition or quality. In particular, melanin-based traits are known to relate to condition and there is a well-characterized genetic pathway underpinning their expression. However, the mechanisms linking variable trait expression to genetic quality remain unclear. One plausible mechanism is that genetic quality could influence trait expression via differential methylation and differential gene expression. We therefore conducted a pilot study examining DNA methylation at a candidate gene (agouti-related neuropeptide:

Indexed as

AgRPcolorationepigeneticsheterozygositymelaninsexual ornament

Identifiers

PMID30038756
PMCPMC6053554
OpenAlexW2806724034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.