Evidence map›Paper›PMID 30038718›Full record

ArticleOncotarget2018

MYC-related microRNAs signatures in non-Hodgkin B-cell lymphomas and their relationships with core cellular pathways.

Giorgio Malpeli, Stefano Barbi, Gabriele Tosadori, Corinna Greco, Simonetta Zupo, Serena Pedron, Matteo Brunelli, Anna Bertolaso, Maria Teresa Scupoli, Mauro Krampera and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. microRNA Profile of High-Grade B-Cell Lymphoma with 11q Aberration.International journal of molecular sciences · 2024
    Article
  4. Article
  5. Review
  6. The role of miR-29 family in disease.Journal of cellular biochemistry · 2021
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. MiRNA Dysregulation in Childhood Hematological Cancer.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Giorgio MalpeliDepartment of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Section of Surgery, University of Verona, Verona, Italy.
Stefano BarbiDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Gabriele TosadoriCenter for BioMedical Computing, University of Verona, Verona, Italy.
Corinna GrecoDepartment of Medicine, Section of Hematology, Stem Cell Research Laboratory, University of Verona, Verona, Italy.
Simonetta ZupoLaboratory of Molecular Diagnostics, IRCCS-AOU San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.
Serena PedronDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Matteo BrunelliDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Anna BertolasoDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Maria Teresa ScupoliDepartment of Medicine, Section of Hematology, University of Verona, Verona, Italy.
Mauro KramperaDepartment of Medicine, Section of Hematology, Stem Cell Research Laboratory, University of Verona, Verona, Italy.
Paul Takam KamgaCenter for BioMedical Computing, University of Verona, Verona, Italy.
Carlo Maria CroceDepartment of Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
George Adrian CalinDepartment of Experimental Therapeutics and The Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Aldo ScarpaDepartment of Diagnostics and Public Health, University of Verona, Verona, Italy.
Alberto ZamòDepartment of Oncology, University of Turin, Torino, Italy.
University of Verona · ITOspedale Policlinico San Martino · ITThe Ohio State University · USThe University of Texas MD Anderson Cancer Center · USUniversity of Turin · IT

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

In order to investigate the role of microRNAs in the pathogenesis of different B-cell lymhoma subtypes, we have applied an array-based assay to a series of 76 mixed non-Hodgkin B-cell lymphomas, including Burkitt's lymphoma (BL), diffuse large B-cell lymphoma, primary mediastinal B-cell lymphoma, mantle cell lymphoma (MCL) and follicular lymphoma. Lymphomas clustered according to histological subtypes, driven by two miRNA clusters (the miR-29 family and the miR-17-92 cluster). Since the two miRNA clusters are known to be MYC-regulated, we investigated whether this would be supported in MYC-driven experimental models, and found that this signature separated BL cell lines and a

Indexed as

cell linesmicroRNAsMYCnetwork analysisnon-Hodgkin B-cell lymphoma

Identifiers

PMID30038718
PMCPMC6049865
OpenAlexW2811398925

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.