Evidence map›Paper›PMID 30038618›Full record

ArticleFrontiers in immunology2018

Thrombin and Plasmin Alter the Proteome of Neutrophil Extracellular Traps.

Chun Hwee Lim, Sunil S Adav, Siu Kwan Sze, Yeu Khai Choong, Rathi Saravanan, Artur Schmidtchen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 81 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Target neutrophil heterogeneity and plasticity in cancer.Journal of hematology & oncology · 2025
    Review
  6. Tandem ssDNA in neutrophil extracellular traps binds thrombin and regulates immunothrombosis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Exploring Neutrophil Extracellular Traps in Cardiovascular Pathologies: The Impact of Lipid Profiles, PAD4, and Radiation.Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Citrulline is not a major determinant of autoantibody reactivity to neutrophil extracellular traps.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  15. Article
  16. Article
  17. Fibrinolytic system and COVID-19: From an innovative view of epithelial ion transport.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Chun Hwee LimInterdisciplinary Graduate School, NTU Institute for Health Technologies, Nanyang Technological University, Singapore, Singapore.
Sunil S AdavLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Siu Kwan SzeSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Yeu Khai ChoongLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Rathi SaravananLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Artur SchmidtchenLee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
Nanyang Technological University · SGLund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophil extracellular traps (NETs) consist of a decondensed DNA scaffold decorated with neutrophil-derived proteins. The proteome of NETs, or "NETome," has been largely elucidated

Indexed as

histonesneutrophil elastaseneutrophil extracellular trapsplasminproteomethrombin

Identifiers

PMID30038618
PMCPMC6046383
OpenAlexW2851380107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.